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Pathways of alpha 1-adrenergic action: comparison with V1-vasopressin and A1-angiotensin.

作者信息

Garcia-Sáinz J A

机构信息

Departamento de Bioenergética, Universidad Nacional Autónoma de México.

出版信息

Circ Res. 1987 Nov;61(5 Pt 2):II1-5.

PMID:2822282
Abstract

The relation between the induction of phosphatidylinositol labelling and ureagenesis by epinephrine (alpha 1-adrenergic action), vasopressin, and angiotensin II was studied in liver cells. It was observed that the alpha 1-adrenergic activation consistently induced a greater stimulation of ureagenesis than the vasopressor peptides. In contrast, vasopressin stimulated phosphatidylinositol labelling to a much greater extent than epinephrine or angiotension II. We suggest that in addition to phosphoinositide turnover, alpha 1-adrenergic action involves other factor(s) in its mechanism of signal transduction.

摘要

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