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HIV感染的干眼症患者泪液细胞因子水平、CD4、CD8计数及HIV病毒载量的纵向分析数据集。

Dataset of longitudinal analysis of tear cytokine levels, CD4, CD8 counts and HIV viral load in dry eye patients with HIV infection.

作者信息

Balne Praveen Kumar, Agrawal Rupesh, Au Veonice Bijin, Lee Bernett, Loo Eileen, Tong Louis, Ghosh Arkasubhra, Teoh Stephen C, Connolly John, Tan Petrina

机构信息

National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore; Singapore Eye Research Institute, Singapore.

Institute of Molecular and Cell Biology, Singapore.

出版信息

Data Brief. 2017 Feb 3;11:152-154. doi: 10.1016/j.dib.2017.01.014. eCollection 2017 Apr.

Abstract

The data presented in this article shows the longitudinal analysis of tear fluid cytokine profiles, blood CD4 and CD8 counts and HIV viral load in 34 dry eye patients with HIV infection during the HAART therapy. Clinical samples were collected from HIV patients with dry eye disease at the time of presentation to the clinic (visit 1), three months (visit 2) and 6 months (visit 3) after the presentation. At each time point tear samples were evaluated for 41 cytokines using Luminex bead based multiplex assay and blood samples were tested for HIV viral load and CD4 and CD8 counts.

摘要

本文呈现的数据显示了对34例接受高效抗逆转录病毒治疗(HAART)的HIV感染干眼症患者泪液细胞因子谱、血液CD4和CD8计数以及HIV病毒载量的纵向分析。临床样本采集自患有干眼症的HIV患者,在其初诊时(就诊1)、初诊后三个月(就诊2)和六个月(就诊3)。在每个时间点,使用基于Luminex微珠的多重检测法对泪液样本中的41种细胞因子进行评估,并对血液样本进行HIV病毒载量以及CD4和CD8计数检测。

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