尼日利亚牛群中的口蹄疫病毒SAT1血清型
Foot-and-mouth disease virus serotype SAT1 in cattle, Nigeria.
作者信息
Ehizibolo D O, Haegeman A, De Vleeschauwer A R, Umoh J U, Kazeem H M, Okolocha E C, Van Borm S, De Clercq K
机构信息
FMD Laboratory, Viral Research Division, National Veterinary Research Institute (NVRI), Vom, Nigeria.
Department of Veterinary Public Health & Preventive Medicine, Faculty of Veterinary Medicine, Ahmadu Bello University, Zaria, Nigeria.
出版信息
Transbound Emerg Dis. 2017 Jun;64(3):683-690. doi: 10.1111/tbed.12629. Epub 2017 Feb 21.
The knowledge of foot-and-mouth disease virus (FMDV) dynamics and epidemiology in Nigeria and the West Africa subregion is important to support local and regional control plans and international risk assessment. Foot-and-mouth disease virus serotype South African territories (SAT)1 was isolated, identified and characterized from an FMD outbreak in cattle in Nigeria in 2015, 35 years after the last report of FMDV SAT1 in West Africa. The VP1 coding sequence of the Nigerian 2015 SAT1 isolates diverges from reported SAT1 topotypes resulting in a separate topotype. The reporting of a novel FMDV SAT1 strain in the virus pool 5 (West and Central Africa) highlights the dynamic and complex nature of FMDV in this region of Africa. Sustained surveillance is needed to understand the origin, the extent and distribution of this novel SAT1 topotype in the region as well as to detect and monitor the occurrence of (re-)emerging FMDV strains.
了解尼日利亚和西非次区域口蹄疫病毒（FMDV）的动态和流行病学情况，对于支持地方和区域防控计划以及国际风险评估至关重要。2015年，在西非最后一次报告口蹄疫病毒SAT1血清型35年后，从尼日利亚牛群的一次口蹄疫疫情中分离、鉴定并表征了口蹄疫病毒南非领土（SAT）1血清型。2015年尼日利亚SAT1分离株的VP1编码序列与已报告的SAT1拓扑型不同，形成了一个单独的拓扑型。在病毒池5（西非和中非）中报告一种新型口蹄疫病毒SAT1毒株，凸显了非洲该地区口蹄疫病毒动态和复杂的性质。需要持续监测，以了解该新型SAT1拓扑型在该地区的起源、范围和分布情况，以及检测和监测（再）出现的口蹄疫病毒毒株的发生情况。
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