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[胃癌根治术后特殊外科并发症的预防要点]

[The key points of prevention for special surgical complications after radical operation of gastric cancer].

作者信息

Xu Hao, Wang Weizhi, Li Panyuan, Zhang Diancai, Yang Li, Xu Zekuan

机构信息

Department of Gastric Surgery, Medical Coordination Innovation Center for Tumor Individualization, The First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China.

出版信息

Zhonghua Wei Chang Wai Ke Za Zhi. 2017 Feb 25;20(2):152-155.

Abstract

Incidence of gastric cancer is high in China and standard radical operation is currently the main treatment for gastric cancer. Postoperative complications, especially some special complications, can directly affect the prognosis of patients, even result in the increase of mortality. But the incidences of these special complications are low, so these complications are often misdiagnosed and delayed in treatment owing to insufficient recognition of medical staff. These special complications include (1) Peterson hernia: It is an abdominal hernia developed in the space between Roux loop and transverse colon mesentery after Roux-Y reconstruction of digestive tract. Peterson hernia is rare and can quickly result in gangrenous ileus. Because of low incidence and without specific clinical symptoms, this hernia does not attract enough attention in clinical practice, so the outcome will be very serious. Once the diagnosis is made, an emergent operation must be performed immediately. Peterson space should be closed routinely in order to avoid the development of hernia. (2) Lymphatic leakage: It is also called chyle leakage. Cisterna chylus is formed by gradual concentration of extensive lymphatic net to diaphragm angle within abdominal cavity. Lymphadenectomy during operation may easily damage lymphatic net and result in leakage. The use of ultrasonic scalpel can decrease the risk of lymphatic leakage in certain degree. If lymphatic leakage is found during operation, transfixion should be performed in time. Treatment includes total parenteral nutrition, maintenance of internal environment, supplement of protein, and observation by clamp as an attempt. (3)Duodenal stump leakage: It is one of serious complications affecting the recovery and leading to death after subtotal gastrectomy. Correct management of duodenal stump during operation is one of key points of the prevention of duodenal stump leakage. Routine purse embedding of duodenal stump is recommend during operation. The key treatment of this complication is to promt diagnosis and effective hemostasis.(4) Blood supply disorder of Roux-Y intestinal loop: Main preventive principle of this complication is to pay attention to the blood supply of vascular arch in intestinal edge. (5) Anastomotic obstruction by big purse of jejunal stump: When Roux-en-Y anastomosis is performed after distal radical operation for gastric cancer, anvil is placed in the remnant stomach and anastomat from distal jejunal stump is placed to make gastrojejunal anastomosis, and the stump is closed with big purse embedding. The embedding jejunal stump may enter gastric cavity leading to internal hernia and anastomotic obstruction. We suggest that application of interruptable and interlocking suture and fixation of stump on the gastric wall can avoid the development of this complication.

摘要

中国胃癌发病率较高,目前标准根治性手术是胃癌的主要治疗方式。术后并发症,尤其是一些特殊并发症,可直接影响患者预后,甚至导致死亡率增加。但这些特殊并发症的发生率较低,常因医务人员认识不足而被误诊和延误治疗。这些特殊并发症包括:(1)彼得森疝:是消化道Roux-Y重建术后在Roux袢与横结肠系膜之间间隙发生的腹外疝。彼得森疝罕见,可迅速导致坏疽性肠梗阻。由于发病率低且无特异性临床症状,该疝在临床实践中未引起足够重视,因此后果会非常严重。一旦确诊,必须立即进行急诊手术。应常规封闭彼得森间隙以避免疝的发生。(2)淋巴漏:又称乳糜漏。乳糜池由腹腔内广泛的淋巴管网逐渐向膈角汇聚形成。手术中淋巴结清扫可能容易损伤淋巴管网而导致淋巴漏。使用超声刀在一定程度上可降低淋巴漏的风险。若术中发现淋巴漏,应及时进行缝扎。治疗包括全胃肠外营养、维持内环境、补充蛋白质,并试行夹闭观察。(3)十二指肠残端漏:是胃大部切除术后影响恢复并导致死亡的严重并发症之一。手术中正确处理十二指肠残端是预防十二指肠残端漏的关键要点之一。手术中建议常规行十二指肠残端荷包包埋。该并发症的关键治疗是早期诊断和有效止血。(4)Roux-Y肠袢血供障碍:该并发症的主要预防原则是注意肠缘血管弓的血供。(5)空肠残端大荷包吻合口梗阻:胃癌根治性远端手术后行Roux-en-Y吻合时,将吻合器砧座置于残胃内,从远端空肠残端置入吻合器进行胃空肠吻合,残端用大荷包包埋关闭。包埋的空肠残端可能进入胃腔导致内疝和吻合口梗阻。我们建议采用间断锁边缝合并将残端固定于胃壁可避免该并发症的发生。

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