Ari Arzu, Fink James B
a Department of Respiratory Therapy , Georgia State University , Atlanta , GA , USA.
Expert Rev Respir Med. 2017 Mar;11(3):201-208. doi: 10.1080/17476348.2017.1289843. Epub 2017 Feb 20.
Inhalation therapy has become a popular procedure for the treatment of patients with tracheostomy. However, clinicians are faced with many challenges during inhalation therapy because of the many factors affecting aerosol therapy to this patient population, and the lack of literature providing guidance in this area of research. Areas covered: The purpose of this paper is to describe the factors affecting aerosol drug delivery to patients with tracheostomy and to explain how to optimize inhalation therapy through device selection, interface selection and delivery technique in this patient population. Expert commentary: Many factors affect inhalation therapy in this patient population and without understanding the impact of these factors on aerosol drug delivery, clinicians will not be able to provide the treatment properly and patients may not benefit from prescribed medications. In the next 5 years, aerosol medicine will continue to experience tremendous growth with new devices and drug/device combinations. However, these advances will have minimal impact on inhalation therapy in patients with tracheostomy unless we provide guidance and training to clinicians on optimizing aerosol drug delivery to this patient population.
吸入疗法已成为治疗气管造口术患者的常用方法。然而,由于影响该患者群体气溶胶治疗的因素众多,且缺乏该领域研究的指导文献,临床医生在吸入治疗过程中面临诸多挑战。涵盖领域:本文旨在描述影响气管造口术患者气溶胶药物递送的因素,并解释如何通过该患者群体的设备选择、接口选择和递送技术来优化吸入治疗。专家评论:许多因素影响该患者群体的吸入治疗,如果不了解这些因素对气溶胶药物递送的影响,临床医生将无法正确提供治疗,患者也可能无法从处方药物中获益。在未来5年,随着新设备以及药物/设备组合的出现,气溶胶医学将继续经历巨大的发展。然而,除非我们为临床医生提供关于优化该患者群体气溶胶药物递送的指导和培训,否则这些进展对气管造口术患者的吸入治疗影响甚微。