Abushwereb Hanan Saaddedin, Elhabash M, Elhamshari S, Eshaefi H
Pharmacology and Clinical Pharmacy Department, University of Tripoli, Faculty of Pharmacy, Tripoli, Libya.
Oncology Department, Tripoli Medical Center, Tripoli, Libya.
Clin Cases Miner Bone Metab. 2016 Sep-Dec;13(3):186-189. doi: 10.11138/ccmbm/2016.13.3.186. Epub 2017 Feb 10.
Negative health effects of aromatase inhibitors (AI) treatments on bones such as osteoporosis are evidenced. This impact of the aromatase inhibitors on bone. This study aimed to improve the medical assistance given to patients under AI treatment to minimize secondary osteoporosis. Fifty Libyan postmenopausal women treated with AI to fight breast cancer were selected from attendants Tripoli Medical Center (TMC), Oncology Department during year 2014. A closed questionnaire was requested from each women including data about age, age at AI therapy, and types of AI, age at bone densitometry measurement, onset and symptoms of osteoporosis, treatment of osteoporosis and measurement of vitamin D and calcium supplement given. The study revealed a poor consideration given to apply the recommendation in cases suffering osteoporosis events. Our results suggest an active implementation of the guidelines concerning the high corporation levels that should be done between oncologist, specialist in osteoporosis, and patients to offer reliable diagnostic and post-therapy follow up.
芳香化酶抑制剂(AI)治疗对骨骼有负面健康影响,如骨质疏松,这已得到证实。芳香化酶抑制剂对骨骼的这种影响。本研究旨在改善接受AI治疗患者的医疗援助,以尽量减少继发性骨质疏松症。2014年,从的黎波里医疗中心(TMC)肿瘤科的就诊者中选取了50名接受AI治疗以对抗乳腺癌的利比亚绝经后妇女。向每位女性发放了一份封闭式问卷,内容包括年龄、开始AI治疗的年龄、AI类型、进行骨密度测量的年龄、骨质疏松症的发病情况和症状、骨质疏松症的治疗以及维生素D和钙补充剂的测量情况。研究发现,在骨质疏松症患者中,对应用相关建议的重视程度较低。我们的结果表明,应积极实施相关指南,即肿瘤学家、骨质疏松症专家和患者之间应进行高度协作,以提供可靠的诊断和治疗后随访。