Cadavid Lina, Sastoque Jorge M, Gutiérrez Carolina, Yabur Mirna, Molina Gustavo
Departments of Pediatric Radiology, Pediatric Cardiology and Oncological Orthopedics, Hospital Pablo Tobón Uribe, Medellín, Colombia.
Universidad CES, Medellin, Colombia.
Radiol Case Rep. 2017 Jan 5;12(1):185-190. doi: 10.1016/j.radcr.2016.11.020. eCollection 2017 Mar.
Burkitt lymphoma (BL) is the most frequent non-Hodgkin lymphoma in pediatric patients, accounting for approximately 34% of the cases of lymphoma in children. This subtype of non-Hodgkin lymphoma was first described in 1958 as a monoclonal proliferation of B cell lymphocytes. Cardiac involvement of BL in association with osseous compromise and lymphadenopathy is rare and poorly documented. We report a case of femur primary BL in an 8-year-old boy with metastatic cardiac involvement, retroperitoneal and iliofemoral lymphadenopathy, and hepatosplenomegaly. We highlight the diagnostic challenge in a patient with clinical nonspecific findings and systemic disease.
伯基特淋巴瘤（BL）是儿科患者中最常见的非霍奇金淋巴瘤，约占儿童淋巴瘤病例的34%。这种非霍奇金淋巴瘤亚型于1958年首次被描述为B淋巴细胞的单克隆增殖。BL合并骨损害和淋巴结病的心脏受累情况罕见且文献记载较少。我们报告一例8岁男孩股骨原发性BL，伴有转移性心脏受累、腹膜后及髂股淋巴结病和肝脾肿大。我们强调了临床无特异性表现及全身性疾病患者的诊断挑战。
