Bokiniec Renata, Własienko Paweł, Borszewska-Kornacka Maria, Szymkiewicz-Dangel Joanna
Neonatal and Intensive Care Department, Medical University of Warsaw, Warsaw, Poland.
Perinatal Cardiology Unit, Medical University of Warsaw, Warsaw, Poland.
Echocardiography. 2017 Apr;34(4):577-586. doi: 10.1111/echo.13489. Epub 2017 Feb 23.
To evaluate right ventricular function in preterm infants with and without bronchopulmonary dysplasia.
Eighty-nine preterm infants (<32 weeks) were divided into three groups: (1) no-bronchopulmonary dysplasia (n=32); (2) mild-bronchopulmonary dysplasia (n=35); (3) severe-bronchopulmonary dysplasia (n=15). Right ventricular echocardiographic parameters included the following: (1) pulsed-wave Doppler through the tricuspid valve (E/A ratio), pulmonary artery acceleration time, right ventricular ejection time, right ventricular velocity-time integral; (2) tissue Doppler measurements of myocardial velocities and atrioventricular conduction times; (3) pulsed-wave Doppler and tissue Doppler evaluation of myocardial performance index and E/E' ratio; and (4) M-mode detection of right ventricular end-diastolic wall diameter.
The severe-bronchopulmonary dysplasia group had higher mean right ventricular myocardial performance index (on the 28th day of life by pulsed-wave Doppler) than the no-bronchopulmonary dysplasia (P=.014) or mild-bronchopulmonary dysplasia (P=.031) groups; no differences were found between no-bronchopulmonary dysplasia and mild-bronchopulmonary dysplasia groups (P=.919). A reduction in right ventricular myocardial performance index at later time points was observed in all three groups (P<.05). We found no differences between preterm infants with differing bronchopulmonary dysplasia severity in other right ventricular echocardiographic parameters.
Right ventricular myocardial performance index measured by pulsed-wave Doppler indicates impaired right ventricular function in preterm infants with severe bronchopulmonary dysplasia.
评估有无支气管肺发育不良的早产儿的右心室功能。
89例孕周小于32周的早产儿被分为三组：（1）无支气管肺发育不良组（n = 32）；（2）轻度支气管肺发育不良组（n = 35）；（3）重度支气管肺发育不良组（n = 15）。右心室超声心动图参数包括：（1）通过三尖瓣的脉冲波多普勒测量（E/A比值）、肺动脉加速时间、右心室射血时间、右心室速度时间积分；（2）心肌速度和房室传导时间的组织多普勒测量；（3）脉冲波多普勒和组织多普勒评估心肌性能指数和E/E'比值；（4）M型检测右心室舒张末期壁直径。
重度支气管肺发育不良组的平均右心室心肌性能指数（出生第28天通过脉冲波多普勒测量）高于无支气管肺发育不良组（P = 0.014）和轻度支气管肺发育不良组（P = 0.031）；无支气管肺发育不良组和轻度支气管肺发育不良组之间未发现差异（P = 0.919）。所有三组在后期时间点右心室心肌性能指数均降低（P < 0.05）。在其他右心室超声心动图参数方面，不同支气管肺发育不良严重程度的早产儿之间未发现差异。
通过脉冲波多普勒测量的右心室心肌性能指数表明重度支气管肺发育不良的早产儿右心室功能受损。
