Bai Yu, Zhou Yi, Lu Xi Hua
Department of Anesthesiology, Henan Cancer Hospital, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, China.
J Cancer Res Ther. 2016 Dec;12(Supplement):C277-C280. doi: 10.4103/0973-1482.200757.
The aim of this study was to observe the efficacy and safety of single-lumen tracheal ventilation for esophageal cancer surgery.
Thirty-eight patients with esophageal carcinoma who prepared for minimally invasive esophagectomy were included in this study. All of the included 38 patients were received single-lumen tracheal ventilation. The arterial blood gas index was monitored through the operation procedure and recorded at four-time points: before induction (T0), at the end of chest operation (T1), at the end of the abdominal operation (T2), and 30 min after extubation (T3). The heart rate (HR) and blood pressure (BP) were also monitored and recorded during the period of PetCO2 >50 mmHg. The agitation incidence rate was also recorded in awakening period.
All the included 38 patients were successfully completed the operation without conversing to open thoracotomy or open laparotomy. The artificial pneumothorax time, artificial pneumoperitoneum time, and operation time were 136.6 ± 26.2 min, 104.4 ± 21.3 min, and 306.7 ± 42.0 min, respectively. The patients' BP and HR was slight elevated but within the normal range (HR <100 breaths/min and BP <140/90 mmHg) when the PetCO2 >50 mmHg. Arterial blood gas results showed that PaCO2 significantly increased in time point of T1, T2, and T3 compared to T0 (P < 0.05); PaO2 significantly increased in time point of T1 and T2 compared to T0 (P < 0.05); HR significantly increased during the operation procedure of the time points T1 (P < 0.05). Of the included 38 patients, 8 were observed preoperative blood gas PaO2 <80 mmHg and the patients had decreased PaO2 in the time point T3 compared to other 30 normal preoperative PaO2 patients. Electrocardiogram monitoring showed that all patients do not appear arrhythmia and myocardial ischemia in the process of surgery. Two of 38 patients were found of mild agitated during waking period.
Single-lumen tracheal ventilation for esophageal cancer surgery is safe and can provide acceptable anesthesia effect.
本研究旨在观察单腔气管通气用于食管癌手术的有效性和安全性。
本研究纳入38例准备行微创食管切除术的食管癌患者。所有38例纳入患者均接受单腔气管通气。在手术过程中监测动脉血气指标,并在四个时间点记录:诱导前(T0)、胸部手术结束时(T1)、腹部手术结束时(T2)和拔管后30分钟(T3)。在呼气末二氧化碳分压(PetCO2)>50 mmHg期间还监测并记录心率(HR)和血压(BP)。在苏醒期记录躁动发生率。
所有38例纳入患者均成功完成手术,未转为开胸或开腹手术。人工气胸时间、人工气腹时间和手术时间分别为136.6±26.2分钟、104.4±21.3分钟和306.7±42.0分钟。当PetCO2>50 mmHg时,患者的血压和心率略有升高,但在正常范围内(HR<100次/分钟,BP<140/90 mmHg)。动脉血气结果显示,与T0相比,T1、T2和T3时间点的动脉血二氧化碳分压(PaCO2)显著升高(P<0.05);与T0相比,T1和T2时间点的动脉血氧分压(PaO2)显著升高(P<0.05);在T1时间点的手术过程中HR显著升高(P<0.05)。在38例纳入患者中,8例术前血气PaO2<80 mmHg,与其他30例术前PaO2正常的患者相比,这些患者在T3时间点的PaO2降低。心电图监测显示,所有患者在手术过程中均未出现心律失常和心肌缺血。38例患者中有2例在苏醒期出现轻度躁动。
单腔气管通气用于食管癌手术是安全的,并且可以提供可接受的麻醉效果。