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半月板移植与支架:文献系统综述

Meniscal Transplants and Scaffolds: A Systematic Review of the Literature.

作者信息

Dangelmajer Sean, Familiari Filippo, Simonetta Roberto, Kaymakoglu Mehmet, Huri Gazi

机构信息

Department of Orthopaedic Surgery, Stanford School of Medicine, Stanford, CA, USA.

Department of Orthopaedic and Trauma Surgery, Magna Græcia University, Catanzaro, Italy.

出版信息

Knee Surg Relat Res. 2017 Mar 1;29(1):3-10. doi: 10.5792/ksrr.16.059.

Abstract

The reported incidence of meniscal tears is approximately 61 per 100,000. In instances where preservation of the native meniscus is no longer a feasible option, meniscal allograft transplantation (MAT) and implants or scaffolds may be considered. The goal of this review was to compare the success and failure rates of two techniques, MAT and meniscal scaffolds, and make an inference which treatment is more preferable at the present time and future. Studies that met inclusion criteria were assessed for technique used, type of transplant used, number of procedures included in the study, mean age of patients, mean follow-up time, number of failures, failure rate, and reported reoperation rate. Fifteen studies for the MAT group and 7 studies for the meniscal scaffold group were identified. In this selection of studies, the average failure rate in the MAT group was 18.7% and average reoperation rate was 31.3%. The average failure rate in the meniscal scaffold group was 5.6%, and average reoperation rate was 6.9%. It appears that although MAT is associated with high reoperation and failure rates, the limited number of studies on both MAT and scaffolds and mainly short-term results of scaffold studies make it difficult to make an objective comparison.

摘要

据报道,半月板撕裂的发病率约为每10万人中有61例。在无法保留天然半月板的情况下,可以考虑同种异体半月板移植(MAT)以及植入物或支架。本综述的目的是比较MAT和半月板支架这两种技术的成功率和失败率,并推断目前和未来哪种治疗方法更可取。对符合纳入标准的研究评估其使用的技术、移植类型、研究中包含的手术数量、患者平均年龄、平均随访时间、失败数量、失败率以及报告的再次手术率。确定了MAT组的15项研究和半月板支架组的7项研究。在这些研究中,MAT组的平均失败率为18.7%,平均再次手术率为31.3%。半月板支架组的平均失败率为5.6%,平均再次手术率为6.9%。虽然MAT与高再次手术率和失败率相关,但关于MAT和支架的研究数量有限,且支架研究主要是短期结果,因此难以进行客观比较。

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