Division of Primary Care, University of Nottingham, Nottingham, UK.
Division of Epidemiology and Public Health, University of Nottingham, Nottingham, UK.
Inj Prev. 2017 Dec;23(6):396-402. doi: 10.1136/injuryprev-2016-042294. Epub 2017 Feb 23.
Maternal depression is common and associated with several child health outcomes. The impact on childhood injuries is underexplored, with existing studies relying on maternal reporting of injury occurrences. Using population healthcare databases from England, we assessed the association between maternal depression and/or anxiety episodes and rates of child poisonings, fractures, burns and serious injuries.
We conducted a prospective cohort study of 207 048 mother-child pairs with linked primary care and hospitalisation data from the Clinical Practice Research Datalink and Hospital Episode Statistics, 1998-2013. Episodes of maternal depression and/or anxiety were identified using diagnoses, prescriptions and hospitalisations, with the child's follow-up time divided into exposed and unexposed periods. Adjusted IRRs (aIRR) for child injury during maternal mental health episodes were estimated using Poisson regression.
54 702 children (26.4%) were exposed to maternal depression and/or anxiety when aged 0-4 years. During follow-up, 2614 poisonings, 6088 fractures and 4201 burns occurred. Child poisoning rates increased during episodes of maternal depression (aIRR 1.52, 95% CI 1.31 to 1.76), depression with anxiety (2.30, 1.93 to 2.75) and anxiety alone (1.63, 1.09 to 2.43). Similarly, rates of burns (1.53, 1.29 to 1.81) and fractures (1.24, 1.06 to 1.44) were greatest during depression with anxiety episodes. There was no association between maternal depression and/or anxiety and serious child injuries.
Maternal depression and/or anxiety episodes were associated with increased rates of child poisonings, fractures and burns. While mechanisms are unclear, prompt identification and treatment of maternal depression and/or anxiety and provision of safety advice (eg, safe medication storage) may reduce child injury risk.
产妇抑郁较为常见,并与多种儿童健康结局相关。其对儿童伤害的影响尚未得到充分探索,现有研究依赖于母亲报告的伤害发生情况。本研究利用来自英格兰的人群医疗保健数据库,评估了产妇抑郁和/或焦虑发作与儿童中毒、骨折、烧伤和严重伤害发生率之间的关系。
我们对 207048 对母子进行了前瞻性队列研究,母子数据来自临床实践研究数据链接和医院入院统计数据库,随访时间为 1998 年至 2013 年。采用诊断、处方和住院记录来识别产妇抑郁和/或焦虑发作,将儿童的随访时间分为暴露期和非暴露期。使用泊松回归估计儿童在产妇精神健康发作期间受伤的调整发病率比(aIRR)。
207048 对母子中,54702 名儿童(26.4%)在 0-4 岁时暴露于产妇抑郁和/或焦虑中。随访期间,有 2614 例中毒、6088 例骨折和 4201 例烧伤发生。儿童中毒发生率在产妇抑郁发作期间(aIRR 1.52,95%CI 1.31-1.76)、抑郁伴焦虑(2.30,1.93-2.75)和单纯焦虑(1.63,1.09-2.43)期间增加。同样,在抑郁伴焦虑发作期间,烧伤(1.53,1.29-1.81)和骨折(1.24,1.06-1.44)的发生率也最高。产妇抑郁和/或焦虑与严重儿童伤害之间没有关联。
产妇抑郁和/或焦虑发作与儿童中毒、骨折和烧伤发生率增加相关。虽然机制尚不清楚,但及时识别和治疗产妇抑郁和/或焦虑,并提供安全建议(例如,安全药物储存)可能会降低儿童受伤风险。