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采用扩大中颅窝入路治疗侧颅底及后颅窝病变

Treatment of Lateral Skull Base and Posterior Cranial Fossa Lesions Utilizing the Extended Middle Cranial Fossa Approach.

作者信息

Roche Joseph P, Goates Andrew J, Hasan David M, Howard Matthew A, Menezes Arnold H, Hansen Marlan R, Gantz Bruce J

机构信息

*Division of Otolaryngology, Department of Surgery, School of Medicine and Public Health, The University of Wisconsin, Madison, Wisconsin †Department of Otolaryngology-Head and Neck Surgery ‡The Department of Neurosurgery, The University of Iowa Carver College of Medicine, The University of Iowa, Iowa City, Iowa.

出版信息

Otol Neurotol. 2017 Jun;38(5):742-750. doi: 10.1097/MAO.0000000000001356.

Abstract

OBJECTIVE

Define the indications and outcomes for subjects undergoing treatment utilizing the extended middle cranial fossa approach (EMCF).

STUDY DESIGN

Retrospective records review.

SETTING

University-based tertiary referral center.

PATIENTS

Subjects undergoing treatment of posterior cranial fossa (PCF) lesions.

INTERVENTION(S): EMCF exposure and treatment of the indicating PCF lesion.

MAIN OUTCOME MEASURE(S): Demographic, audiometric, and cranial nerve functioning variables were assessed.

RESULTS

Thirty-five subjects who underwent an EMCF exposure were identified over a 12-year period. The most common indication was meningioma (18; 51%) followed by schwannomas (six, 17%), and vascular lesions (five, 14%). Preoperative cranial nerve complaints were common (32, 94%) as were objective cranial nerve abnormalities on physical examination (21; 60%). Preoperative audiometric data from subjects with hearing demonstrated good functioning including pure-tone average (PTA) (21.7 ± 15.6 dB HL) and word understanding scores (95.1 ± 7.4%). Most (34, 97%) subjects had intact facial nerve function. The average length of stay was 11.6 days (median = 9). Cranial neuropathies were common postoperatively with 27 (79%) subjects demonstrating some objective cranial nerve dysfunction, the most common of which was trigeminal nerve hypesthesia (21, 61.7%). Subjects with identifiable pre- and postoperative audiometric data and preoperative hearing demonstrated small declines in the four-tone average (16.2 dB) and word recognition scores (22.4%). Two subjects (6%) had new profound hearing loss postoperatively.

CONCLUSIONS

The EMCF approach can provide safe and effective exposure of the anterior PCF.

摘要

目的

明确采用扩大中颅窝入路(EMCF)进行治疗的患者的适应证及治疗结果。

研究设计

回顾性病历审查。

研究地点

大学附属三级转诊中心。

患者

接受后颅窝(PCF)病变治疗的患者。

干预措施

采用EMCF暴露并治疗相应的PCF病变。

主要观察指标

评估人口统计学、听力测定及颅神经功能变量。

结果

在12年期间,共确定了35例行EMCF暴露的患者。最常见的适应证是脑膜瘤(18例,51%),其次是神经鞘瘤(6例,17%)和血管病变(5例,14%)。术前颅神经症状常见(32例,94%),体格检查时客观颅神经异常也常见(21例,60%)。有听力的患者术前听力测定数据显示功能良好,包括纯音平均听阈(PTA)(21.7±15.6dB HL)和言语理解得分(95.1±7.4%)。大多数(34例,97%)患者面神经功能完整。平均住院时间为11.6天(中位数=9天)。术后颅神经病变常见,27例(79%)患者存在一些客观颅神经功能障碍,最常见的是三叉神经感觉减退(21例,61.7%)。有可识别的术前和术后听力测定数据且术前有听力的患者,其四音平均听阈(下降16.2dB)和言语识别得分(下降22.4%)有小幅下降。2例(6%)患者术后出现新的重度听力丧失。

结论

EMCF入路可安全有效地暴露PCF前部。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e124/6719683/13727eeda943/nihms-845560-f0001.jpg

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本文引用的文献

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A new standardized format for reporting hearing outcome in clinical trials.一种新的用于临床试验中听力结果报告的标准化格式。
Otolaryngol Head Neck Surg. 2012 Nov;147(5):803-7. doi: 10.1177/0194599812458401. Epub 2012 Aug 29.
3
Petroclival meningiomas: multimodality treatment and outcomes at long-term follow-up.岩斜区脑膜瘤:多模态治疗及长期随访结果
Neurosurgery. 2007 Jun;60(6):965-79; discussion 979-81. doi: 10.1227/01.NEU.0000255472.52882.D6.
7
Hearing preservation with the transcrusal approach to the petroclival region.经岩骨入路至岩斜区时的听力保留
Otol Neurotol. 2004 Jul;25(4):594-8; discussion 598. doi: 10.1097/00129492-200407000-00029.
8
The evolution of surgical approaches for posterior fossa meningiomas.后颅窝脑膜瘤手术入路的演变
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