Synthesis of sandwich-like molybdenum sulfide/mesoporous organosilica nanosheets for photo-thermal conversion and stimuli-responsive drug release.

Sandwich-like molybdenum sulfide/mesoporous organosilica nanosheets (denoted as MoS@MOS) have been prepared for the first time via direct growth of ethane-bridged mesostructured organosilica on MoS nanosheets by using cetyltrimethylammonium bromide (CTAB) as structure directing agent. The obtained MoS@MOS nanosheets possess well-defined sandwich-like structure, high surface area (∼920cm/g), uniform pore size (∼4.2nm), large pore volume (∼1.41cmg). In vitro cytotoxicity assessments demonstrate that the MoS@MOS nanosheets have excellent biocompatibility. Owing to the encapsulation of the MoS, the obtained MoS@MOS nanosheets have photo-thermal conversion capability and photo-thermally controlled drug release property. These properties make the MoS@MOS nanosheets promising for biomedical applications.