Badarudeen Sameer, Shu Albert C, Ong Kevin L, Baykal Doruk, Lau Edmund, Malkani Arthur L
Orthopaedic Surgery & Sports Medicine Department, University of Kentucky, Bowling Green, Kentucky.
Department of Orthopedic Surgery, University of Louisville, KentuckyOne Health, Louisville, Kentucky.
J Arthroplasty. 2017 Jun;32(6):1954-1958. doi: 10.1016/j.arth.2017.01.037. Epub 2017 Feb 1.
The purpose of this study was to identify the incidence and types of complications after revision total hip arthroplasty (THA) within the first year, and determine the relative risk factors for these complications and of re-revision.
The sample size of 5% Medicare claims data from 1998-2011 was studied. Primary THA patients who underwent subsequent revision were identified using ICD-9-CM codes. Outcomes and complications after revision THA were assessed. Multivariate Cox regression was used to evaluate the effect of patient demographic characteristics on the adjusted complication risk for revision THA patients.
Of the 64,260 primary THA patients identified between 1998 and 2011, 3555 patients (5.71%) underwent revision THA. Etiology of primary hip failure included mechanical complications such as loosening and wear (40.7%), dislocation (14.0%), and infection (11.3%). Complications after revision THA included infection and redo revision, 17.3% and 15.8% followed by venous thromboembolic disease (VTE) at 11.1%, dislocation at 5.43%, PE at 3.24%, and death at 2.11%. The rate of "new" infections after an aseptic revision was 8.13%. Patients in the 85+-year-old age group had a 100% greater adjusted risk of VTE (P < .001) and 406% higher adjusted risk of death (P < .001) than those in the 65-69 years-old age group. Patients with higher Charlson scores had higher adjusted risks of VTE (P < .001), infection (P < .001), death (P = .002), and re-revision THA (P = .011).
Advanced age is a clear risk factor for VTE and mortality, but not for dislocation, infection, or re-revision. Higher Charlson index was found to be a risk factor for every complication after revision except dislocation. Greater attention is required to address the high rate of infection and re-do revision after revision THA (17.3% and 15.8%).
本研究的目的是确定翻修全髋关节置换术(THA)后第一年内并发症的发生率和类型,并确定这些并发症及再次翻修的相关危险因素。
研究了1998 - 2011年5%医疗保险理赔数据的样本量。使用ICD - 9 - CM编码识别接受后续翻修的初次THA患者。评估翻修THA后的结局和并发症。采用多变量Cox回归评估患者人口统计学特征对翻修THA患者调整后并发症风险的影响。
在1998年至2011年间识别出的64260例初次THA患者中,3555例(5.71%)接受了翻修THA。初次髋关节置换失败的病因包括机械性并发症,如松动和磨损(40.7%)、脱位(14.0%)和感染(11.3%)。翻修THA后的并发症包括感染和再次翻修,分别为17.3%和15.8%,其次是静脉血栓栓塞性疾病(VTE),发生率为11.1%,脱位发生率为5.43%,肺栓塞(PE)发生率为3.24%,死亡率为2.11%。无菌性翻修后“新”感染率为8.13%。85岁及以上年龄组患者的VTE调整风险比65 - 69岁年龄组患者高100%(P < 0.001),死亡调整风险高406%(P < 0.001)。Charlson评分较高的患者发生VTE(P < 0.001)、感染(P < 0.001)、死亡(P = 0.002)和再次翻修THA(P = 0.011)的调整风险更高。
高龄是VTE和死亡率的明确危险因素,但不是脱位、感染或再次翻修的危险因素。发现较高的Charlson指数是翻修后除脱位外每种并发症的危险因素。需要更加关注翻修THA后较高的感染率和再次翻修率(分别为17.3%和15.8%)。