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在感染性和无菌性翻修全髋关节置换术中,高手术量医院并不比低手术量医院表现更好:基于荷兰关节置换登记处的再翻修风险和死亡率分析。

High-volume hospitals do not perform better than low-volume hospitals in septic and aseptic revision total hip arthroplasty: an analysis of re-revision risk and mortality based on the Dutch Arthroplasty Register.

作者信息

Vink Marije C, Peters Rinne M, Van Dooren Bart, Deen Amarens, Van Steenbergen Liza N, Schreurs B Wim, Zijlstra Wierd P

机构信息

Department of Orthopedic Surgery, Medical Center Leeuwarden; Department of Orthopedic Surgery, University Medical Center Groningen, the Netherland.

Department of Orthopedic Surgery, Flinders Medical center, Adelaide, Australia.

出版信息

Acta Orthop. 2025 Aug 15;96:625-631. doi: 10.2340/17453674.2025.44331.

Abstract

BACKGROUND AND PURPOSE

Revision total hip arthroplasty (rTHA) is a complex procedure that may benefit from centralization. We examined the association between annual hospital volume of rTHA and re-revision risk and mortality.

METHODS

We included all rTHAs between 2007 and 2022 in general hospitals, registered in the Dutch Arthroplasty Register (LROI; n = 12,515). Hospitals were categorized into low (< 25 rTHA/year) or high volume (≥ 25 rTHA/year). Competing-risk analyses and Cox proportional hazard regression analyses were performed to assess implant re-revision and Kaplan-Meier survival analysis for mortality. Results were stratified into septic (permanent Girdlestone, 1-stage, and 2-stage revisions) and aseptic first revisions.

RESULTS

1-stage septic revisions showed a higher risk of re-revision in high-volume hospitals (hazard ratio [HR] 1.6, 95% confidence interval [CI] 1.1-2.4). We found no difference in re-revision risk after DAIR (HR 1.1, CI 0.9-1.3). 2-stage septic revisions were more often performed in high-volume hospitals (5% vs 2%). There was no statistical difference in re-revision rates between hospitals after revision for aseptic loosening (HR 1.1, CI 0.9-1.4), dislocation (HR 1.1, CI 0.9-1.4), and periprosthetic fractures (HR 1.1, CI 0.8-1.5). Mortality showed no differences between groups, neither for septic nor aseptic revisions.

CONCLUSION

There was no difference between high-volume hospitals and low-volume hospitals regarding risk for re-revision after aseptic loosening, dislocation and periprosthetic fracture, and septic DAIR and mortality. In high-volume hospitals, 1-stage septic revisions was associated with a significantly higher re-revision risk. 2-stage revisions are more frequent in high-volume hospitals, indicating more complex pathology.

摘要

背景与目的

翻修全髋关节置换术(rTHA)是一项复杂的手术,集中化处理可能有益。我们研究了rTHA的年度医院手术量与再次翻修风险及死亡率之间的关联。

方法

我们纳入了200年至2022年在荷兰关节置换登记处(LROI)登记的综合医院中的所有rTHA手术(n = 12,515)。医院被分为低手术量(每年<25例rTHA)或高手术量(每年≥25例rTHA)。进行竞争风险分析和Cox比例风险回归分析以评估植入物再次翻修情况,并进行Kaplan-Meier生存分析以评估死亡率。结果被分层为感染性(永久性Girdlestone、1期和2期翻修)和无菌性初次翻修。

结果

在高手术量医院中,1期感染性翻修显示出更高的再次翻修风险(风险比[HR] 1.6,95%置信区间[CI] 1.1 - 2.4)。我们发现在清创、抗生素和保留植入物(DAIR)术后再次翻修风险没有差异(HR 1.1,CI 0.9 - 1.3)。2期感染性翻修在高手术量医院中更常进行(5%对2%)。在因无菌性松动、脱位和假体周围骨折进行翻修后,医院之间的再次翻修率没有统计学差异(HR 1.1,CI 0.9 - 1.4)(脱位:HR 1.1,CI 0.9 - 1.4;假体周围骨折:HR 1.1,CI 0.8 - 1.5)。无论是感染性还是无菌性翻修,各组之间的死亡率均无差异。

结论

在无菌性松动、脱位和假体周围骨折以及感染性DAIR和死亡率方面,高手术量医院和低手术量医院之间的再次翻修风险没有差异。在高手术量医院中,1期感染性翻修与显著更高的再次翻修风险相关。2期翻修在高手术量医院中更频繁,表明病理情况更复杂。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bcb/12357176/229e9c7b5bdf/ActaO-96-44331-g001.jpg

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