Farag Mina, Arif Rawa, Sabashnikov Anton, Zeriouh Mohamed, Popov Aron-Frederik, Ruhparwar Arjang, Schmack Bastian, Dohmen Pascal M, Szabó Gábor, Karck Matthias, Weymann Alexander
Department of Cardiac Surgery, Heart and Marfan Center - University of Heidelberg, Heidelberg, Germany.
Department of Cardiothoracic Surgery, Heart Center, University of Cologne, Cologne, Germany.
Med Sci Monit. 2017 Feb 25;23:1017-1025. doi: 10.12659/msm.900841.
BACKGROUND Long-term follow-up data concerning isolated tricuspid valve pathology after replacement or reconstruction is limited. Current American Heart Association guidelines equally recommend repair and replacement when surgical intervention is indicated. Our aim was to investigate and compare operative mortality and long-term survival in patients undergoing isolated tricuspid valve repair surgery versus replacement. MATERIAL AND METHODS Between 1995 and 2011, 109 consecutive patients underwent surgical correction of tricuspid valve pathology at our institution for varying structural pathologies. A total of 41 (37.6%) patients underwent tricuspid annuloplasty/repair (TAP) with or without ring implantation, while 68 (62.3%) patients received tricuspid valve replacement (TVR) of whom 36 (53%) were mechanical and 32 (47%) were biological prostheses. RESULTS Early survival at 30 days after surgery was 97.6% in the TAP group and 91.1% in the TVR group. After 6 months, 89.1% in the TAP group and 87.8% in the TVR group were alive. In terms of long-term survival, there was no further mortality observed after one year post surgery in both groups (Log Rank p=0.919, Breslow p=0.834, Tarone-Ware p=0.880) in the Kaplan-Meier Survival analysis. The 1-, 5-, and 8-year survival rates were 85.8% for TAP and 87.8% for TVR group. CONCLUSIONS Surgical repair of the tricuspid valve does not show survival benefit when compared to replacement. Hence valve replacement should be considered generously in patients with reasonable suspicion that regurgitation after repair will reoccur.
关于三尖瓣置换或重建术后孤立性三尖瓣病变的长期随访数据有限。美国心脏协会当前指南同样建议,在需要进行手术干预时,修复和置换均可采用。我们的目的是调查和比较接受孤立性三尖瓣修复手术与置换手术患者的手术死亡率和长期生存率。
1995年至2011年期间,我们机构连续109例患者因不同的结构病变接受了三尖瓣病变的手术矫正。共有41例(37.6%)患者接受了三尖瓣环成形术/修复术(TAP),伴或不伴环植入,而68例(62.3%)患者接受了三尖瓣置换术(TVR),其中36例(53%)使用机械瓣膜,32例(47%)使用生物假体。
TAP组术后30天的早期生存率为97.6%,TVR组为91.1%。6个月后,TAP组的生存率为89.1%,TVR组为87.8%。在Kaplan-Meier生存分析中,两组术后一年均未观察到进一步的死亡(对数秩检验p = 0.919,Breslow检验p = 0.834,Tarone-Ware检验p = 0.880)。TAP组和TVR组的1年、5年和8年生存率分别为85.8%和87.8%。
与置换相比,三尖瓣手术修复未显示出生存优势。因此,对于合理怀疑修复后反流会复发的患者,应充分考虑瓣膜置换。