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二尖瓣置换术中轻-中度功能性三尖瓣反流行瓣环成形术的长期结果:我们是否应该对三尖瓣行瓣环成形术还是让其保持原样?

Long-term results of annuloplasty in trivial-to-mild functional tricuspid regurgitation during mitral valve replacement: should we perform annuloplasty on the tricuspid valve or leave it alone?

机构信息

Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.

Department of Thoracic and Cardiovascular Surgery, Sejong General Hospital, Bucheon, Korea.

出版信息

Eur J Cardiothorac Surg. 2018 Apr 1;53(4):756-763. doi: 10.1093/ejcts/ezx395.

Abstract

OBJECTIVES

The benefits of concomitant tricuspid annuloplasty (TAP) for non-significant functional tricuspid regurgitation (TR) during mitral valve replacement (MVR) are controversial. We evaluated the long-term outcomes-particularly the long-term tricuspid valve (TV) functional outcomes-of MVR with or without tricuspid ring annuloplasty.

METHODS

From 2004 to 2014, 256 patients (56.4 ± 12.1 years) with trivial or mild functional TR who underwent MVR were enrolled. Eighty-two patients underwent concomitant tricuspid ring annuloplasty (TAP group), and 174 patients did not undergo the TV procedure (nTAP group). Propensity score-matched analysis was performed (n = 72 in each group). The follow-up duration was 77.4 ± 42.4 months.

RESULTS

The early clinical outcomes were similar between the 2 groups before and after propensity score matching with an early mortality rate of 3.5% (9 of 256). No patients experienced ring-related complications during follow-up. Eleven (6.3%) patients developed significant TR (≥moderate) in the nTAP group, while no patients developed significant TR in the TAP group. There were no significant differences in overall survival between the 2 groups before or after matching. However, propensity score-matched analysis revealed that the freedom from significant TR aggravation and freedom from TV-related event rates were significantly higher in the TAP group than in the nTAP group (P = 0.047 and P = 0.043, respectively).

CONCLUSIONS

Patients with untreated trivial or mild functional TR accompanied by mitral valve disease can develop significant TR during follow-up. TV ring annuloplasty can be performed without complications and can be beneficial for patients with trivial or mild functional TR who are undergoing MVR.

摘要

目的

在二尖瓣置换术(MVR)期间同期行三尖瓣环成形术(TAP)治疗非重度功能性三尖瓣反流(TR)的获益仍存在争议。我们评估了 MVR 同期或非同期行三尖瓣环成形术的长期结果,尤其是长期三尖瓣(TV)功能结局。

方法

2004 年至 2014 年,我们纳入了 256 例(56.4±12.1 岁)行 MVR 的轻或中度功能性 TR 患者。82 例行同期三尖瓣环成形术(TAP 组),174 例未行 TV 手术(nTAP 组)。采用倾向评分匹配分析(每组 n=72)。随访时间为 77.4±42.4 个月。

结果

两组患者在倾向评分匹配前后的早期临床结局相似,早期死亡率为 3.5%(256 例中 9 例)。随访期间无患者发生环相关并发症。nTAP 组中有 11 例(6.3%)患者发生重度 TR(≥中度),而 TAP 组中无患者发生重度 TR。两组患者在匹配前后的总生存率无显著差异。然而,倾向评分匹配分析显示,TAP 组患者中重度 TR 加重和 TV 相关事件的无事件生存率明显高于 nTAP 组(P=0.047 和 P=0.043)。

结论

伴有二尖瓣疾病的未治疗轻或中度功能性 TR 患者在随访过程中可能会发展为重度 TR。TV 环成形术可以安全进行,并且对于行 MVR 的轻或中度功能性 TR 患者可能有益。

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