Ackland F M, Stanhope R, Preece M A
Department of Growth and Development, Institute of Child Health, London.
Arch Dis Child. 1987 Oct;62(10):1077-8. doi: 10.1136/adc.62.10.1077.
A 14-year old girl presented with growth failure and Cushing's disease. Histological examination confirmed a craniopharyngioma but failed to show that the tumour secreted adrenocorticotrophic hormone. We suggest that her Cushing's disease was caused by hypothalamic dysfunction associated with increased corticotrophin-releasing hormone secretion, secondary to the craniopharyngioma.
一名14岁女孩出现生长发育迟缓及库欣病。组织学检查确诊为颅咽管瘤,但未显示该肿瘤分泌促肾上腺皮质激素。我们认为她的库欣病是由颅咽管瘤继发的促肾上腺皮质激素释放激素分泌增加相关的下丘脑功能障碍所致。