Orczykowski Michał, Derejko Paweł, Urbanek Piotr, Bodalski Robert, Kodziszewska Katarzyna, Sierpiński Radosław, Baranowski Rafał, Bilińska Maria, Szumowski Łukasz
Arrhythmia Department, National Institute of Cardiology, Warsaw.
Medicover Hospital, Cardiology Department, Warsaw, Poland.
J Heart Valve Dis. 2016 Sep;25(5):574-579.
Re-entrant atrial arrhythmias are common in patients after cardiac surgery. To date, however, no studies have reported the safety and efficacy of radiofrequency (RF) ablation of macro-re-entrant atrial arrhythmias in a unique, homogeneous group of patients after surgical replacement of the aortic valve and single right atriotomy.
Among over 4,000 RF catheter ablations performed at the authors' center between 2008 and 2014, eight patients (seven males, one female; mean age 55.1 ± 19.9 years) after aortic valve replacement (AVR) and without history of any other cardiosurgical procedures were identified with documented macro-re-entrant atrial arrhythmia. The mechanism of macro-re-entrant arrhythmia was analyzed, as well as the safety and efficacy of RF ablation in a group of patients after AVR and single right atrial free wall atriotomy.
The average time from surgery to RF catheter ablation was 11.3 ± 11.3 years (range: 4-35 years). In five patients with permanent arrhythmia, entrainment mapping proved these arrhythmias to be cavotricuspid isthmus- dependent, in three patients with paroxysmal atrial arrhythmia cavotricuspid isthmus-dependent atrial flutter was induced during the electrophysiological study. Intra-atrial re-entrant tachycardia was neither recorded nor induced in any patient. Successful ablation of cavotricuspid isthmus is defined as the termination of arrhythmia, and bidirectional block in cavotricuspid isthmus was achieved in all patients. A long-term follow up, based on a seven-day Holter monitoring, was conducted in all patients, with a mean observation time of 40.1 ± 28.6 months after the procedure. Among the patients, ablated arrhythmia (cavotricuspid isthmusdependent atrial flutter) recurred in one patient, atrial fibrillation occurred in three patients, and an atrial tachycardia in one patient.
In the presented series of patients, cavotricuspid isthmus-dependent atrial flutter was shown to be the mechanism of post-cardiosurgical macro-re-entrant clinical arrhythmia in all subjects. Atrial fibrillation was frequently observed among those patients during follow up.
折返性房性心律失常在心脏手术后的患者中很常见。然而,迄今为止,尚无研究报道在主动脉瓣置换术和单次右心房切开术后这一独特、同质的患者群体中,射频(RF)消融治疗大折返性房性心律失常的安全性和有效性。
在作者所在中心2008年至2014年期间进行的4000多次射频导管消融术中,确定了8例主动脉瓣置换术(AVR)后且无任何其他心脏手术史的患者(7例男性,1例女性;平均年龄55.1±19.9岁),他们记录有大折返性房性心律失常。分析了大折返性心律失常的机制,以及AVR和单次右心房游离壁切开术后一组患者中射频消融的安全性和有效性。
从手术到射频导管消融的平均时间为11.3±11.3年(范围:4 - 35年)。在5例永久性心律失常患者中,拖带标测证实这些心律失常依赖于腔静脉 - 三尖瓣峡部;在3例阵发性房性心律失常患者中,电生理研究期间诱发了依赖于腔静脉 - 三尖瓣峡部的房扑。在任何患者中均未记录到或诱发房内折返性心动过速。成功消融腔静脉 - 三尖瓣峡部定义为心律失常终止,所有患者均实现了腔静脉 - 三尖瓣峡部的双向阻滞。对所有患者进行了基于7天动态心电图监测的长期随访,术后平均观察时间为40.1±28.6个月。在这些患者中,1例患者消融的心律失常(依赖于腔静脉 - 三尖瓣峡部的房扑)复发,3例患者发生房颤,1例患者发生房性心动过速。
在本系列患者中,所有受试者术后大折返性临床心律失常的机制均为依赖于腔静脉 - 三尖瓣峡部的房扑。在这些患者随访期间经常观察到房颤。