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小儿急诊科出院时的心动过速是否值得关注?一项非同期队列研究。

Is Tachycardia at Discharge From the Pediatric Emergency Department a Cause for Concern? A Nonconcurrent Cohort Study.

作者信息

Wilson Paria M, Florin Todd A, Huang Guixia, Fenchel Matthew, Mittiga Matthew R

机构信息

Division of Emergency Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

Division of Emergency Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

出版信息

Ann Emerg Med. 2017 Sep;70(3):268-276.e2. doi: 10.1016/j.annemergmed.2016.12.010. Epub 2017 Feb 24.

Abstract

STUDY OBJECTIVE

We evaluate the association between discharge tachycardia and (1) emergency department (ED) and urgent care revisit and (2) receipt of clinically important intervention at the revisit.

METHODS

The study included a nonconcurrent cohort of children aged 0 to younger than 19 years, discharged from 2 pediatric EDs and 4 pediatric urgent care centers in 2013. The primary exposure was discharge tachycardia (last recorded pulse rate ≥99th percentile for age). The main outcome was ED or urgent care revisit within 72 hours of discharge. Additional outcomes included interventions received and disposition at the revisit, prevalence of discharge tachycardia at the index visit, and associations of pain, fever, and medications with discharge tachycardia. Multivariable logistic regression determined relative risk ratios for revisit and receipt of clinically important intervention at the revisit.

RESULTS

Of eligible visits, 126,774 were included, of which 10,470 patients (8.3%) had discharge tachycardia. Discharge tachycardia was associated with an increased risk of revisit (adjusted RR 1.3; 95% confidence interval 1.2 to 1.5), increased risk of tachycardia at the revisit (relative risk 3.1; 95% confidence interval 2.6 to 3.7), and of the receipt of certain clinically important interventions (supplemental oxygen, respiratory medications and admission, antibiotics and admission, and peripheral intravenous line placement and admission). However, there was no increased risk for the composite outcome of receipt of any clinically important intervention or admission on revisit.

CONCLUSION

Discharge tachycardia is associated with an increased risk of revisit. It is likely that tachycardia at discharge is not a critical factor associated with impending physiologic deterioration.

摘要

研究目的

我们评估出院时心动过速与以下两项之间的关联:(1)急诊科(ED)复诊及紧急护理复诊;(2)复诊时接受具有临床重要意义的干预措施。

方法

本研究纳入了一个非同期队列,研究对象为2013年从两家儿科急诊科和四家儿科紧急护理中心出院的0至19岁以下儿童。主要暴露因素为出院时心动过速(最后记录的脉搏率≥年龄对应的第99百分位数)。主要结局为出院后72小时内的急诊科或紧急护理复诊。其他结局包括复诊时接受的干预措施及处置情况、首次就诊时出院心动过速的患病率,以及疼痛、发热和药物与出院心动过速的关联。多变量逻辑回归确定复诊及复诊时接受具有临床重要意义的干预措施的相对风险比。

结果

在符合条件的就诊病例中,共纳入126,774例,其中10,470例患者(8.3%)出院时心动过速。出院时心动过速与复诊风险增加相关(校正风险比1.3;95%置信区间1.2至1.5),复诊时心动过速风险增加(相对风险3.1;95%置信区间2.6至3.7),以及接受某些具有临床重要意义的干预措施(补充氧气、使用呼吸药物并住院、使用抗生素并住院,以及放置外周静脉导管并住院)相关。然而,复诊时接受任何具有临床重要意义的干预措施或住院的综合结局风险并未增加。

结论

出院时心动过速与复诊风险增加相关。出院时心动过速可能并非与即将发生的生理恶化相关的关键因素。

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