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人类健康风险评估中的变异性和不确定性建模。

Modeling of variability and uncertainty in human health risk assessment.

作者信息

Dutta Palash

机构信息

Dept. of Mathematics, Dibrugarh University, Dibrugarh, 786004, India.

出版信息

MethodsX. 2017 Jan 31;4:76-85. doi: 10.1016/j.mex.2017.01.005. eCollection 2017.

Abstract

Health risk assessments have been carried out worldwide to examine potential health risk due to exposure to toxic contaminants in various environments. In risk assessment, it is most important to know the nature of all available information, data or model parameters. It is observed that available information/data are tainted with uncertainty and variability in the same time, i.e., uncertainty and variability co-exist. In such situation it is important to devise method for processing both uncertainty and variability into same framework and which is an open issue. In this regards, this paper presents an algorithm to combined approach to propagate variability and uncertainty in the same framework. The differences and advantages of this algorithm over the existing methods are presented below: •The representation of uncertain model parameters are probabilistic together with generalized fuzzy numbers and normal interval valued fuzzy numbers.•The results obtained are then interpreted in terms of p-box and fuzzy numbers.•The advantage of this approach over the existing methods is that this approach gives an accurate resultant fuzzy number which is of trapezoidal type generalized fuzzy number that is different from the existing methods.

摘要

全球范围内都进行了健康风险评估,以检查因接触各种环境中的有毒污染物而产生的潜在健康风险。在风险评估中,了解所有可用信息、数据或模型参数的性质至关重要。据观察,可用信息/数据同时受到不确定性和变异性的影响,即不确定性和变异性并存。在这种情况下,设计一种将不确定性和变异性纳入同一框架的处理方法很重要,而这是一个尚未解决的问题。在这方面,本文提出了一种算法,用于在同一框架中传播变异性和不确定性的组合方法。该算法与现有方法的差异和优势如下:•不确定模型参数的表示采用概率形式,同时结合广义模糊数和正态区间值模糊数。•然后根据p盒和模糊数对所得结果进行解释。•该方法相对于现有方法的优势在于,该方法给出了一个准确的结果模糊数,它是梯形类型的广义模糊数,这与现有方法不同。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2c8/5318352/81cc23c8319c/fx1.jpg

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