de Jager C R, Moont R J, Pearce N E
Faculty of Medicine, University of the Free State, Bloemfontein, South Africa.
The Ruth and Bruce Rappaport Faculty of Medicine, Technicon, Israel Institute of Technology, Haifa, Israel.
S Afr J Surg. 2016 Jun;54(2):4-7.
Venous thromboembolism (VTE) is a complex and serious condition, with high morbidity and mortality, especially in hospitalised patients. Yet its diagnosis remains challenging because of its unspecific clinical presentation. The objective of this study was to apply an algorithmic combination approach to diagnosing VTE by the addition of a D-dimer assay and Wells' criteria for our hospital's internal referral forms requesting compression ultrasound (CUS), to determine the effect on the number of referrals for CUS and the incidence of deep vein thrombosis (DVT) diagnoses.
Inpatients who had been referred to the hospital's vascular laboratory and who had undergone a CUS to exclude an acute lower limb DVT were retrospectively analysed between January 2009 and December 2013, and compared to prospectively collected data for the full year (2014) after the introduction of the new referral form. Comparisons included the mean annual number of referrals for CUS and the incidence of DVT diagnoses.
The hospital incidence of diagnosed DVTs for 2009-2013 was 0.17%, compared to 0.16% for 2014 (ρ = 0.930). In contrast, the total number of referrals for CUS as a percentage of all hospital admissions dropped from 0.84% in 2009-2013 to 0.63% in 2014 (ρ = 0.009, odds ratio 0.76, 95% confidence interval: 0.62-0.93).
The implementation of Wells' criteria and D-dimer to the new request form for CUS significantly decreased referrals to the hospital's vascular laboratory without impacting on the number of DVT cases diagnosed. This is a positive change which simplifies care and reduces the expense of ultrasonography investigations.
静脉血栓栓塞症(VTE)是一种复杂且严重的病症,发病率和死亡率都很高,尤其是在住院患者中。然而,由于其临床表现缺乏特异性,其诊断仍然具有挑战性。本研究的目的是通过在我院要求进行加压超声检查(CUS)的内部转诊表中增加D - 二聚体检测和Wells标准,应用算法组合方法来诊断VTE,以确定对CUS转诊数量和深静脉血栓形成(DVT)诊断发生率的影响。
回顾性分析2009年1月至2013年12月期间转诊至我院血管实验室并接受CUS以排除急性下肢DVT的住院患者,并与引入新转诊表后全年(2014年)前瞻性收集的数据进行比较。比较内容包括CUS的年均转诊数量和DVT诊断的发生率。
2009 - 2013年确诊DVT的医院发病率为0.17%,2014年为0.16%(ρ = 0.930)。相比之下,CUS转诊总数占所有住院患者的百分比从2009 - 2013年的0.84%降至2014年的0.63%(ρ = 0.009,优势比0.76,95%置信区间:0.62 - 0.93)。
在CUS的新申请表中实施Wells标准和D - 二聚体显著减少了转诊至我院血管实验室的数量,而不影响DVT病例的诊断数量。这是一个积极的变化,简化了护理并降低了超声检查的费用。