Soliman Ramy S, Lee Sanghoon, Eun Seulgi, Mohamed Abdalla Z, Lee Jeungchan, Lee Eunyoung, Makary Meena M, Kathy Lee Seung Min, Lee Hwa-Jin, Choi Woo Suk, Park Kyungmo
aDepartment of Biomedical Engineering, Kyung Hee University, Yongin bDepartment of Clinical Korean Medicine, Graduate School cDepartment of Radiology dSchool of Dance, Kyung Hee University, Seoul eMibyeong Research Center, Korea Institute of Oriental Medicine (KIOM), Daejeon, South Korea fDepartment of Systems and Biomedical Engineering, Faculty of Engineering, Cairo University, Giza, Egypt gDepartment of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, Massachusetts, USA.
Neuroreport. 2017 Mar 22;28(5):285-291. doi: 10.1097/WNR.0000000000000758.
Motor imagery (MI) has attracted increased interest for motor rehabilitation as many studies have shown that MI shares the same neural networks as motor execution (ME). Nevertheless, MI in terms of facial movement has not been studied extensively; thus, in the present study, we investigated shared neural networks between facial motor imagery (FMI) and facial motor execution (FME). In addition, FMI somatotopy within-face was investigated between the forehead and the mouth. Functional MRI was used to examine 34 healthy individuals with ME and MI paradigms for the forehead and the mouth. The general linear model and a paired t-test were performed to define the facial area in the primary motor cortex (M1) and this area has been used to investigate somatotopy between the forehead and mouth FMI. FMI recruited similar brain motor areas as FME, but showed less neural activity in all activated regions. The facial areas in M1 were distinguishable from other body movements such as finger movement. Further investigation of this area showed that forehead and mouth imagery tended to lack a somatotopic representation for position on M1, and yet had distinct characteristics in terms of neural activity level. FMI showed different characteristics from general MI as the former exclusively activated facial processing areas. In addition, FME and FMI showed different characteristics in terms of BOLD signal level, while sharing the same neural areas. The results imply a potential usefulness of MI training for rehabilitation of facial motor disease considering that forehead and mouth somatotopy showed no clear position difference, and yet showed a significant BOLD signal intensity variation.
运动想象（MI）在运动康复领域引起了越来越多的关注，因为许多研究表明，运动想象与运动执行（ME）共享相同的神经网络。然而，关于面部运动的运动想象尚未得到广泛研究；因此，在本研究中，我们调查了面部运动想象（FMI）和面部运动执行（FME）之间共享的神经网络。此外，还研究了前额和嘴巴之间面部运动想象的面部躯体定位。使用功能磁共振成像（fMRI）对34名健康个体进行前额和嘴巴的运动执行与运动想象范式检查。采用一般线性模型和配对t检验来确定初级运动皮层（M1）中的面部区域，并使用该区域来研究前额和嘴巴面部运动想象之间的躯体定位。面部运动想象激活的脑运动区域与面部运动执行相似，但在所有激活区域的神经活动较少。M1中的面部区域与手指运动等其他身体运动区域不同。对该区域的进一步研究表明，前额和嘴巴的想象在M1上的位置往往缺乏躯体定位表征，但在神经活动水平方面具有明显特征。面部运动想象与一般运动想象表现出不同的特征，因为前者仅激活面部处理区域。此外，面部运动执行和面部运动想象在血氧水平依赖（BOLD）信号水平方面表现出不同特征，同时共享相同的神经区域。考虑到前额和嘴巴的躯体定位没有明显的位置差异，但显示出显著的BOLD信号强度变化，这些结果暗示了运动想象训练对面部运动疾病康复的潜在作用。
