不明原因发热的成年患者中的噬血细胞综合征：一种不常见的肺结核表现：病例报告
Haemophagocytic syndrome in an adult suffering from pyrexia of unknown origin: an uncommon presentation of tuberculosis: a case report.
作者信息
Haque Wasim Md Mohosin Ul, Shuvo Md Erfanur Rahman, Rahim Muhammad Abdur, Mitra Palash, Samad Tabassum, Haque Jalaluddin Ashraful
机构信息
Department of Nephrology and Dialysis, Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM) General Hospital, Dhaka, 1000, Bangladesh.
Ibrahim Medical College, Shahbag, Dhaka, 1000, Bangladesh.
出版信息
BMC Res Notes. 2017 Feb 27;10(1):110. doi: 10.1186/s13104-017-2434-y.
BACKGROUND
Tuberculosis is common, can involve various organs of the body and may have diverse presentations. Haemophagocytic syndrome is one of the rare presentations of tuberculosis carrying a very high mortality. Early detection and institution of anti-tuberculosis medications can be life-saving.
CASE PRESENTATION
A 23-year-old Bengali man presented with prolonged fever, weight loss, hepatosplenomegaly, pancytopenia and altered liver function. He had high erythrocyte sedimentation rate, positive tuberculin test, granuloma in liver biopsy, and haemophagocytosis was evidenced by histopathological examination of bone marrow. He recovered with anti-tuberculosis therapy.
CONCLUSION
This case demonstrates that consideration of tuberculosis as an underlying cause of haemophagocytic syndrome could be rewarding and life-saving in this rapidly fatal condition.
背景
结核病很常见，可累及身体的各个器官，且表现形式多样。噬血细胞综合征是结核病罕见的表现形式之一，死亡率极高。早期发现并使用抗结核药物可能挽救生命。
病例报告
一名23岁的孟加拉男子出现长期发热、体重减轻、肝脾肿大、全血细胞减少及肝功能改变。他红细胞沉降率升高、结核菌素试验呈阳性、肝活检有肉芽肿，骨髓组织病理学检查证实有噬血细胞现象。他接受抗结核治疗后康复。
结论
该病例表明，在这种迅速致命的疾病中，将结核病视为噬血细胞综合征的潜在病因可能会有成效且挽救生命。
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