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气道内支架置入术:一种治疗小儿气道阻塞的可靠技术

External stenting: A reliable technique to relieve airway obstruction in small children.

机构信息

Sakakibara Heart Institute, Tokyo, Japan.

Ginza Heart Clinic, Tokyo, Japan.

出版信息

J Thorac Cardiovasc Surg. 2017 May;153(5):1167-1177. doi: 10.1016/j.jtcvs.2016.12.041. Epub 2017 Feb 3.

Abstract

OBJECTIVE

Airway obstruction in children may be caused by conditions such as vascular compression and congenital tracheobronchomalacia. Obstructive pulmonary vascular disease may be a detrimental sequel for patients with congenital heart disease. We evaluate our own original external stenting technique as a treatment option for these patients.

METHODS

Ninety-eight patients underwent external stenting (1997-2015). Cardiovascular anomalies were noted in 82 (83.7%). Nine patients had hypoplastic left heart syndrome and 6 had other types of single-ventricular hearts.

RESULTS

The median age at the first operation was 7.2 months (range, 1.0-77.1 months). The mechanisms were tracheobronchomalacia with (n = 46) or without (n = 52) vascular compression. Patients underwent 127 external stentings for 139 obstruction sites (62 trachea, 55 left bronchus, and 22 right bronchus). The stent sizes varied from 12 to 16 mm. There were 14 (8 in the hospital and 6 after discharge) mortality cases. Nine required reoperation for restenosis and 3 required stent removal for infection. The actuarial freedom from mortality and any kind of reoperation was 74.7% ± 4.6% after 2.8 years. The negative pressure threshold to induce airway collapse for congenital malacia (n = 58) improved from -15.9 to -116.0 cmHO. A follow-up computed tomography scan (>2.0 years interval from the operation; n = 23) showed the mean diameter of the stented segment at 88.5% ± 13.7% (bronchus) and 94.5% ± 8.2% (trachea) of the reference.

CONCLUSIONS

External stenting is a reliable method to relieve airway compression for small children, allowing an age-proportional growth of the airway.

摘要

目的

儿童的气道阻塞可能由血管压迫和先天性气管支气管软化等原因引起。阻塞性肺血管疾病可能是先天性心脏病患者的不利后果。我们评估了我们自己的原创外部支架技术作为这些患者的治疗选择。

方法

98 名患者接受了外部支架治疗(1997-2015 年)。82 例(83.7%)存在心血管畸形。9 例患有左心发育不全综合征,6 例患有其他类型的单心室心脏。

结果

首次手术的中位年龄为 7.2 个月(范围为 1.0-77.1 个月)。机制为气管支气管软化伴(n=46)或不伴(n=52)血管压迫。患者接受了 127 次外部支架置入术,共治疗 139 个阻塞部位(62 个气管,55 个左支气管,22 个右支气管)。支架尺寸从 12 毫米到 16 毫米不等。有 14 例(8 例在医院内,6 例在出院后)死亡。9 例因再狭窄需要再次手术,3 例因感染需要取出支架。2.8 年后,无死亡和任何类型再手术的生存率为 74.7%±4.6%。先天性软化的气道塌陷负压阈值(n=58)从-15.9 厘米水柱改善至-116.0 厘米水柱。23 例(手术间隔时间>2.0 年;n=23)的随访 CT 扫描显示,支架段的平均直径为参考值的 88.5%±13.7%(支气管)和 94.5%±8.2%(气管)。

结论

外部支架是一种可靠的方法,可以缓解小儿气道压迫,使气道随年龄比例生长。

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