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先天性心脏缺陷幼儿的气道梗阻与呼吸机依赖:自膨式金属支架的作用

Airway obstruction and ventilator dependency in young children with congenital cardiac defects: a role for self-expanding metal stents.

作者信息

Kumar Pankaj, Roy Amit, Penny Daniel J, Ladas George, Goldstraw Peter

机构信息

Thoracic Surgery, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK.

出版信息

Intensive Care Med. 2002 Feb;28(2):190-5. doi: 10.1007/s00134-001-1184-3. Epub 2002 Jan 15.

Abstract

OBJECTIVE

Young children with congenital cardiac defect and airway obstruction leading to ventilator dependency present a significant clinical challenge with uncertain outcome.

DESIGN

Retrospective review of our experience with self-expanding metal stents in these young children between 1996-2000.

RESULTS

Airway stenting has been undertaken in five such children (four boys, one girl) at our institution. Their mean age was 7.4 months (range 2-14 months), and four of the five had undergone congenital cardiac surgery and could not be weaned from the ventilator following surgery. These five children were ventilator dependent for a mean of 112 days (range 40-210 days, median 71). A total of ten self-expanding metal stents were inserted (4-11 mm in diameter and 15-33 mm in length). The sites stented included the trachea (two stents), the left main bronchus (three stents) and the bronchus intermedius (five stents). Four of these five children were successfully weaned from the ventilator and extubated after a mean time interval of 6 days (range 2-11 days, median 5.5) after stenting. One child failed to wean from the ventilator, required tracheostomy and is ventilator dependent after 8 months. There was one death 2 months after extubation but unrelated to the airway. Three children remain well and asymptomatic 24, 36 and 54 months after stenting.

CONCLUSIONS

Airway stenting in such young children is an infrequent procedure often undertaken in dire circumstances. We have found it valuable in enabling ventilator-dependent children to be extubated with encouraging early results. Their long-term outlook remains uncertain and is dependent on the underlying cardiac status.

摘要

目的

患有先天性心脏缺陷和气道阻塞并导致依赖呼吸机的幼儿面临重大临床挑战,预后不确定。

设计

回顾性分析我们在1996年至2000年间对这些幼儿使用自膨式金属支架的经验。

结果

我们机构对5名此类儿童(4名男孩,1名女孩)进行了气道支架置入术。他们的平均年龄为7.4个月(范围2至14个月),5名儿童中有4名接受了先天性心脏手术,术后无法脱离呼吸机。这5名儿童平均依赖呼吸机112天(范围40至210天,中位数71天)。共置入了10个自膨式金属支架(直径4至11毫米,长度15至33毫米)。置入支架的部位包括气管(2个支架)、左主支气管(3个支架)和中间支气管(5个支架)。这5名儿童中有4名在置入支架后平均6天(范围2至11天,中位数5.5天)成功脱离呼吸机并拔管。1名儿童未能脱离呼吸机,需要进行气管切开术,8个月后仍依赖呼吸机。有1例在拔管后2个月死亡,但与气道无关。3名儿童在置入支架后24、36和54个月情况良好且无症状。

结论

在此类幼儿中进行气道支架置入术是一种不常见的操作,通常在危急情况下进行。我们发现它对于使依赖呼吸机的儿童能够拔管很有价值,早期结果令人鼓舞。他们的长期前景仍不确定,取决于潜在的心脏状况。

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