一名曾有三次氯氮平相关性血液系统异常发作史的患者成功再次使用氯氮平治疗。
Successful clozapine re-challenge in a patient with three previous episodes of clozapine-associated blood dyscrasia.
作者信息
Foster Jessica, Lally John, Bell Victoria, Shergill Sukhi
机构信息
, MB BCh, National Psychosis Unit, South London and Maudsley NHS Foundation Trust, London, UK.
, MB MSc MRCPsych, South London and Maudsley NHS Foundation Trust, London, UK; Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK; National Psychosis Unit, Department of Psychiatry, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin, Ireland.
出版信息
BJPsych Open. 2017 Feb 9;3(1):22-25. doi: 10.1192/bjpo.bp.116.003467. eCollection 2017 Jan.
UNLABELLED
A case is presented of a 30-year-old female with treatment-resistant schizoaffective disorder who was referred to a tertiary-level specialist psychosis service. We describe the history of clozapine trials and associated episodes of agranulocytosis and neutropenia, followed by the successfully tolerated third clozapine re-challenge within our service.
DECLARATION OF INTEREST
None.
COPYRIGHT AND USAGE
© The Royal College of Psychiatrists 2017. This is an open access article distributed under the terms of the Creative Commons Non-Commercial, No Derivatives (CC BY-NC-ND) license.
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本文介绍了一名30岁患有难治性分裂情感障碍的女性病例，该患者被转诊至三级专科精神病服务机构。我们描述了氯氮平试验的病史以及相关的粒细胞缺乏症和中性粒细胞减少症发作，随后在我们的服务机构中患者成功耐受了第三次氯氮平重新挑战。
利益声明
无。
版权与使用
© 皇家精神病学院2017年。这是一篇开放获取文章，根据知识共享非商业性、无衍生作品（CC BY-NC-ND）许可条款分发。
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