Touleimat Salma, Darwish Basma, Vassilieff Maud, Stochino Loi Emanuela, Hennetier Clotilde, Roman Horace
Department of Gynecology and Obstetrics, Rouen University Hospital, Rouen, France.
Division of Gynecology and Obstetrics, Department of Surgical Sciences, University of Cagliari, Cagliary, Italy.
Minerva Ginecol. 2017 Oct;69(5):440-446. doi: 10.23736/S0026-4784.17.04031-X. Epub 2017 Feb 27.
The study aimed to estimate the growth rate of abdominal wall endometriosis (AWE) following cesarean section (CS), in order to potentially identify a growth model of endometriosis in vivo.
This monocentric, retrospective study included 23 patients presenting 26 nodules of post-CS AWE treated by surgical excision. Nodule surface and volume, time-lapse between surgery and AWE as well as the contraception used were noted. A comparison between nodules' features was performed depending on hormonal vs. non-hormonal contraception.
The time-lapse between CS and AWE surgery had a mean value of 48 months. The mean surface of an AWE nodule was of 3.83 cm2, and the mean volume was of 5.32 cm3. Comparison between the main surface and volume in patients receiving hormonal vs. non-hormonal contraception was statistically non-significant. No statistically significant correlation between AWE dimension and time was revealed. In patients presenting more than one lesion, nodules appeared to grow following variable patterns.
AWE natural history was characterized by inter- and intra-individual variability, independently of the method of contraception used.
本研究旨在评估剖宫产术后腹壁子宫内膜异位症（AWE）的生长速率，以便有可能确定体内子宫内膜异位症的生长模型。
这项单中心回顾性研究纳入了23例接受手术切除治疗的剖宫产术后AWE结节患者，共26个结节。记录结节的表面积和体积、手术与AWE之间的时间间隔以及所使用的避孕方法。根据激素避孕与非激素避孕对结节特征进行比较。
剖宫产与AWE手术之间的时间间隔平均值为48个月。AWE结节的平均表面积为3.83平方厘米，平均体积为5.32立方厘米。接受激素避孕与非激素避孕患者的主要表面积和体积比较在统计学上无显著差异。未发现AWE大小与时间之间存在统计学上的显著相关性。在出现多个病灶的患者中，结节似乎呈现出不同的生长模式。
AWE的自然病程具有个体间和个体内的变异性，与所使用的避孕方法无关。
