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减少空气中颗粒物暴露对呼吸健康益处的前瞻性评估。

Prospective evaluation of respiratory health benefits from reduced exposure to airborne particulate matter.

作者信息

Hao Yanhui, Zhang Guanghui, Han Bin, Xu Xiaowen, Feng Nannan, Li Yong, Wang Wei, Kan Haidong, Bai Zhipeng, Zhu Yiliang, Au William, Xia Zhao-Lin

机构信息

a Department of Occupational and Environmental Health, School of Public Health , Fudan University , Shanghai , China.

b State Key Laboratory of Environmental Criteria and Risk Assessment , Chinese Research Academy of Environmental Sciences , Beijing , China.

出版信息

Int J Environ Health Res. 2017 Apr;27(2):126-135. doi: 10.1080/09603123.2017.1292497. Epub 2017 Feb 16.

DOI:10.1080/09603123.2017.1292497
PMID:28245677
Abstract

We aimed to investigate if short-term exposure to reduced particulate matter (PM) air pollution would affect respiratory function in healthy adults. We followed a cohort of 42 healthy participants from a community afflicted with severe PM air pollution to a substantially less polluted area for nine days. We measured daily airborne PM [with an aerodynamic diameter of less than 2.5 μm (PM) and 10 μm (PM)] and PM carbon component concentrations. Five repeated respiratory function measurements and fractional exhaled nitric oxide test were made for each participant. Associations between respiratory health and PM exposure were assessed using linear mixed models. Each 10 μg/m decrease in same-day PM was associated with small but consistent increase in the forced expiratory volume in 1 s (FEV) (9.00 mL) and forced vital capacity (14.35 mL). Our observations indicate that respiratory health benefits can be achieved even after a short-term reduction of exposure to PM. Our results provide strong evidence for more rigorous air pollution controls for the health benefit of populations.

摘要

我们旨在研究短期暴露于减少的颗粒物(PM)空气污染是否会影响健康成年人的呼吸功能。我们追踪了一群42名健康参与者,他们从一个遭受严重PM空气污染的社区来到一个污染程度大幅降低的地区,为期九天。我们测量了每日空气中的PM[空气动力学直径小于2.5μm(PM)和10μm(PM)]以及PM碳成分浓度。对每位参与者进行了五次重复的呼吸功能测量和呼出一氧化氮分数测试。使用线性混合模型评估呼吸健康与PM暴露之间的关联。当日PM每降低10μg/m,1秒用力呼气量(FEV)(9.00mL)和用力肺活量(14.35mL)会有小但持续的增加。我们的观察结果表明,即使短期减少PM暴露也能实现呼吸健康益处。我们的结果为更严格的空气污染控制以造福人群健康提供了有力证据。

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