Alyaev Yu G, Pshikhachev A M, Shpot E V, Akopyan G N, Proskura A V
Department of Urology, Sechenov First Moscow State Medical University, Research Institute of Uronephrology and Human Reproductive Health, Moscow, the RF.
Urologiia. 2016 Aug(3):104-106.
There is conflicting evidence on the impact of urolithiasis on the risk of developing cancer of kidney and upper urinary tract. Most researchers are of the opinion that there is a definite association between the diseases and clinicians should take the necessary measures to detect possible malignancy of the kidney and upper urinary tract in patients with urolithiasis at the earliest stages. However, the pathophysiological mechanisms that may underlie the development of renal cell carcinoma and urothelial cancer in patients with urolithiasis remain unexplored.
关于尿路结石对肾和上尿路癌症发生风险的影响，证据相互矛盾。大多数研究人员认为，这些疾病之间存在明确关联，临床医生应采取必要措施，尽早检测尿路结石患者肾和上尿路可能存在的恶性肿瘤。然而，尿路结石患者肾细胞癌和尿路上皮癌发生可能的病理生理机制仍未得到探索。
