Kekonen Atte, Bergelin Mikael, Eriksson Jan-Erik, Vaalasti Annikki, Ylänen Heimo, Viik Jari
Faculty of Biomedical Sciences and Engineering, Tampere University of Technology, Tampere, Finland. BioMediTech Institute, Tampere University of Technology, Tampere, Finland.
Physiol Meas. 2017 Jun 22;38(7):1373-1383. doi: 10.1088/1361-6579/aa63d6.
Our group has developed a bipolar bioimpedance measurement-based method for determining the state of wound healing. The objective of this study was to assess the capability of the method.
To assess the performance of the method, we arranged a follow-up study of four acute wounds. The wounds were measured using the method and photographed throughout the healing process.
Initially the bioimpedance of the wounds was significantly lower than the impedance of the undamaged skin, used as a baseline. Gradually, as healing progressed, the wound impedance increased and finally reached the impedance of the undamaged skin.
The clinical appearance of the wounds examined in this study corresponded well with the parameters derived from the bioimpedance data.
Hard-to-heal wounds are a significant and growing socioeconomic burden, especially in the developed countries, due to aging populations and to the increasing prevalence of various lifestyle related diseases. The assessment and the monitoring of chronic wounds are mainly based on visual inspection by medical professionals. The dressings covering the wound must be removed before assessment; this may disturb the wound healing process and significantly increases the work effort of the medical staff. There is a need for an objective and quantitative method for determining the status of a wound without removing the wound dressings. This study provided evidence of the capability of the bioimpedance based method for assessing the wound status. In the future measurements with the method should be extended to concern hard-to-heal wounds.
我们的团队开发了一种基于双极生物阻抗测量的方法来确定伤口愈合状态。本研究的目的是评估该方法的能力。
为了评估该方法的性能,我们对四个急性伤口进行了随访研究。在整个愈合过程中,使用该方法对伤口进行测量并拍照。
最初,伤口的生物阻抗显著低于用作基线的未受损皮肤的阻抗。随着愈合的进展,伤口阻抗逐渐增加,最终达到未受损皮肤的阻抗。
本研究中检查的伤口的临床外观与从生物阻抗数据得出的参数非常吻合。
难愈合伤口是一个重大且不断增加的社会经济负担,尤其是在发达国家,这是由于人口老龄化以及与各种生活方式相关疾病的患病率不断上升所致。慢性伤口的评估和监测主要基于医护人员的目视检查。在评估前必须去除覆盖伤口的敷料;这可能会干扰伤口愈合过程,并显著增加医护人员的工作量。需要一种无需去除伤口敷料就能客观定量地确定伤口状态的方法。本研究提供了基于生物阻抗的方法评估伤口状态能力的证据。未来,应将该方法的测量扩展到难愈合伤口。