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仿生柔性传感器及其在人体健康检测中的应用

Biomimetic Flexible Sensors and Their Applications in Human Health Detection.

作者信息

Yu Huiwen, Li Hao, Sun Xidi, Pan Lijia

机构信息

Collaborative Innovation Center of Advanced Microstructures, School of Electronic Science and Engineering, Nanjing University, Nanjing 210093, China.

出版信息

Biomimetics (Basel). 2023 Jul 6;8(3):293. doi: 10.3390/biomimetics8030293.

DOI:10.3390/biomimetics8030293
PMID:37504181
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10807369/
Abstract

Bionic flexible sensors are a new type of biosensor with high sensitivity, selectivity, stability, and reliability to achieve detection in complex natural and physiological environments. They provide efficient, energy-saving and convenient applications in medical monitoring and diagnosis, environmental monitoring, and detection and identification. Combining sensor devices with flexible substrates to imitate flexible structures in living organisms, thus enabling the detection of various physiological signals, has become a hot topic of interest. In the field of human health detection, the application of bionic flexible sensors is flourishing and will evolve into patient-centric diagnosis and treatment in the future of healthcare. In this review, we provide an up-to-date overview of bionic flexible devices for human health detection applications and a comprehensive summary of the research progress and potential of flexible sensors. First, we evaluate the working mechanisms of different classes of bionic flexible sensors, describing the selection and fabrication of bionic flexible materials and their excellent electrochemical properties; then, we introduce some interesting applications for monitoring physical, electrophysiological, chemical, and biological signals according to more segmented health fields (e.g., medical diagnosis, rehabilitation assistance, and sports monitoring). We conclude with a summary of the advantages of current results and the challenges and possible future developments.

摘要

仿生柔性传感器是一种新型生物传感器，具有高灵敏度、选择性、稳定性和可靠性，可在复杂的自然和生理环境中实现检测。它们在医疗监测与诊断、环境监测以及检测与识别等方面提供了高效、节能且便捷的应用。将传感器器件与柔性基板相结合，以模仿生物体中的柔性结构，从而能够检测各种生理信号，已成为一个备受关注的热门话题。在人体健康检测领域，仿生柔性传感器的应用正蓬勃发展，并将在未来医疗保健中演变为以患者为中心的诊断和治疗方式。在这篇综述中，我们提供了用于人体健康检测应用的仿生柔性器件的最新概述，以及对柔性传感器研究进展和潜力的全面总结。首先，我们评估不同类别的仿生柔性传感器的工作机制，描述仿生柔性材料的选择与制造及其优异的电化学特性；然后，我们根据更细分的健康领域（如医学诊断、康复辅助和运动监测）介绍一些用于监测物理、电生理、化学和生物信号的有趣应用。我们最后总结了当前成果的优势以及面临的挑战和未来可能的发展方向。

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