Jasuja Guneet K, Bhasin Shalender, Rose Adam J
aCenter for Healthcare Organization and Implementation Research (CHOIR), ENRM VAMC, Bedford. bDepartment of Health Law, Policy and Management, Boston University School of Public Health, Boston cResearch Program in Men's Health, Aging and Metabolism, Boston Claude D. Pepper Older Americans Independence Center, Brigham and Women's Hospital, Harvard Medical School, Boston dRAND Corporation, Boston, MA eDepartment of Medicine, Section of General Internal Medicine, Boston University School of Medicine, Boston, Massachusetts, USA.
Curr Opin Endocrinol Diabetes Obes. 2017 Jun;24(3):240-245. doi: 10.1097/MED.0000000000000336.
There has been an increase in the prescribing of testosterone therapy in the past decade. There is concern that at least part of this increase is driven by advertising rather than sound medical practice. The purpose of this review is to summarize the recent trends in testosterone prescribing, and to examine whether testosterone is being appropriately prescribed as per guidelines.
Both global and U.S. data reflect an overall increase in the use of testosterone in the last decade, although there are early signs of a decline in testosterone sales since 2014. This increased prescribing has been accompanied with an overall increase in testing for testosterone levels, prescription of testosterone without the appropriate diagnostic evaluation recommended by clinical practice guidelines, and apparent use of this therapy for unproven medical conditions.
Research to date suggests that there is room to improve our prescribing of testosterone. Greater understanding of the potential provider-level and system-level factors that contribute to the current prescribing practices may help accomplish such improvement.
在过去十年中，睾酮疗法的处方量有所增加。人们担心这种增加至少部分是由广告驱动的，而非基于合理的医疗实践。本综述的目的是总结睾酮处方的近期趋势，并根据指南检查睾酮的处方是否恰当。
全球和美国的数据均反映出过去十年中睾酮使用的总体增加，尽管自2014年以来有睾酮销售额下降的早期迹象。这种处方量的增加伴随着睾酮水平检测的总体增加、在未进行临床实践指南推荐的适当诊断评估的情况下开具睾酮处方，以及明显将该疗法用于未经证实的医疗状况。
迄今为止的研究表明，我们在睾酮处方方面仍有改进空间。更好地理解导致当前处方实践的潜在提供者层面和系统层面因素可能有助于实现这种改进。
