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[由神经科医生首次诊断的5例中枢神经系统粟粒性结核瘤临床报告]

[A clinical report of five cases of central nervous system miliary tuberculomas first diagnosed by neurologists].

作者信息

Huang X, Wang X Y, Zhu Z H, Qi X K, Yu Y X

机构信息

Department of Neurology, Navy General Hospital of PLA, Beijing 100048, China.

出版信息

Zhonghua Nei Ke Za Zhi. 2017 Mar 1;56(3):205-207. doi: 10.3760/cma.j.issn.0578-1426.2017.03.011.

Abstract

To explore the clinical characteristics and imaging features of miliary tuberculomas in central nervous system(CNS). A total of 5 cases diagnosed with tuberculosis in CNS first diagnosed by neurologists in Navy General Hospital of PLA were enrolled in the study. All clinical and imaging data were collected and analyzed retrospectively. The main initial symptoms were fever and headache (4/5). Multiple diffused miliary lesions were shown by brain MRI, with maximum diameter ranged from 1-4 mm and ring-shape or nodular enhancement after gadolinium injection. As mycobacterium tuberculosis could seldomly be found in serum and cerebrospinal fluid, contrast MRI remains the effective method for detecting miliary tuberculomas in CNS.

摘要

探讨中枢神经系统(CNS)粟粒性结核瘤的临床特征及影像学特点。选取解放军海军总医院神经科初诊为中枢神经系统结核的5例患者纳入研究。回顾性收集并分析所有临床及影像学资料。主要首发症状为发热和头痛(4/5)。脑部MRI显示多发弥漫性粟粒样病灶,最大直径1 - 4mm,注射钆后呈环形或结节状强化。由于血清及脑脊液中很少能发现结核分枝杆菌,对比增强MRI仍是检测中枢神经系统粟粒性结核瘤的有效方法。

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