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回顾梗阻性左半结肠癌的治疗:评估术中结肠灌洗后一期切除吻合术的可行性。

Reviewing the Management of Obstructive Left Colon Cancer: Assessing the Feasibility of the One-stage Resection and Anastomosis After Intraoperative Colonic Irrigation.

作者信息

Awotar Gavish Kumar, Guan Guoxin, Sun Wei, Yu Hongliang, Zhu Ming, Cui Xinye, Liu Jie, Chen Jiaxi, Yang Baoshun, Lin Jianyu, Deng Zeyong, Luo Jianwei, Wang Chen, Nur Osman Abdifatah, Dhiman Pankaj, Liu Pixu, Luo Fuwen

机构信息

Department of General Surgery, The Second Affiliated Hospital of Dalian Medical University, Dalian City, Liaoning Province, PR China.

Department of General Surgery, The Third Affiliated Hospital of Dalian Medical University, Dalian City, Liaoning Province, PR China.

出版信息

Clin Colorectal Cancer. 2017 Jun;16(2):e89-e103. doi: 10.1016/j.clcc.2016.12.001. Epub 2017 Jan 18.

Abstract

BACKGROUND

The management of obstructive left colon cancer (OLCC) remains debatable with the single-stage procedure of primary colonic anastomosis after cancer resection and on-table intracolonic lavage now being supported.

PATIENTS AND METHODS

Patients with acute OLCC who were admitted between January 2008 and January 2015 were distributed into 5 different groups. Group ICI underwent emergency laparotomy for primary anastomosis following colonic resection and intraoperative colonic lavage; Group HP underwent emergency Hartmann's Procedure; Group CON consisted of patients treated by conservative management with subsequent elective open cancer resection; Group COL were colostomy patients; and Group INT consisted of patients who had interventional radiology followed by open elective colon cancer resection. The demographics of the patients and comorbidity, intraoperative data, and postoperative data were collected, with P < .05 as significant.

RESULTS

There were 4 deaths in 138 cases (2.90%). There was only 1 patient who had anastomotic leakage (5.56%) in Group ICI, compared with none in Group HP and Group COL, 1 case in Group INT (7.69%), and 2 cases in Group CON (6.06%) (P > .05). Group INT and Group CON, when compared to the three surgical groups, Groups ICI, Group COL, and Group HP, individually, were statistically significant for the duration of surgery (P < .05).

CONCLUSIONS

Primary anastomosis following colonic resection after irrigation can be safely performed in selected patients, with the necessary surgical expertise, with no increased risk in mortality, anastomotic leakage, and other postoperative complications.

摘要

背景

梗阻性左半结肠癌(OLCC)的治疗仍存在争议,目前支持在癌症切除后进行一期结肠吻合术及术中结肠灌洗的单阶段手术方法。

患者与方法

2008年1月至2015年1月收治的急性OLCC患者被分为5个不同组。ICI组在结肠切除及术中结肠灌洗后行急诊剖腹术进行一期吻合;HP组行急诊Hartmann手术;CON组为接受保守治疗随后择期行开放性癌症切除术的患者;COL组为结肠造口患者;INT组为由介入放射学治疗后再行择期开放性结肠癌切除术的患者。收集患者的人口统计学资料及合并症、术中数据和术后数据,P <.05为有统计学意义。

结果

138例患者中有4例死亡(2.90%)。ICI组仅有1例发生吻合口漏(5.56%),HP组和COL组无吻合口漏,INT组有1例(7.69%),CON组有2例(6.06%)(P >.05)。与三个手术组(ICI组、COL组和HP组)相比,INT组和CON组在手术时长方面具有统计学意义(P <.05)。

结论

在具备必要手术专业知识的情况下,经灌洗后结肠切除一期吻合术可在选定患者中安全进行,且不增加死亡、吻合口漏及其他术后并发症的风险。

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