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The Phospholamban Journey 4 Decades After Setting Out for Ithaka.

作者信息

Kranias Evangelia G, Hajjar Roger J

机构信息

From the Department of Pharmacology and Cell Biophysics, University of Cincinnati College of Medicine, OH (E.G.K.); and Cardiovascular Research Center, Department of Cardiology, Icahn School of Medicine at Mount Sinai, New York, NY (R.J.H.).

出版信息

Circ Res. 2017 Mar 3;120(5):781-783. doi: 10.1161/CIRCRESAHA.116.310007.

Abstract
摘要

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本文引用的文献

2
The structural basis for phospholamban inhibition of the calcium pump in sarcoplasmic reticulum.
J Biol Chem. 2013 Oct 18;288(42):30181-30191. doi: 10.1074/jbc.M113.501585. Epub 2013 Aug 31.
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Modulation of cardiac contractility by the phospholamban/SERCA2a regulatome.
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Circulation. 2009 Mar 10;119(9):1241-52. doi: 10.1161/CIRCULATIONAHA.108.783852. Epub 2009 Feb 23.
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A mutation in the human phospholamban gene, deleting arginine 14, results in lethal, hereditary cardiomyopathy.
Proc Natl Acad Sci U S A. 2006 Jan 31;103(5):1388-93. doi: 10.1073/pnas.0510519103. Epub 2006 Jan 23.
8
Dilated cardiomyopathy and heart failure caused by a mutation in phospholamban.
Science. 2003 Feb 28;299(5611):1410-3. doi: 10.1126/science.1081578.
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Physiol Rev. 1998 Oct;78(4):921-47. doi: 10.1152/physrev.1998.78.4.921.
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Phospholamban regulates the Ca2+-ATPase through intramembrane interactions.
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