Tian Chao, Chen Lie, Zhu Caiyi
Department of Ultrasound, Affiliated Haikou Hospital, Xiangya School of Medicine, Central South University, Haikou 570000, China.
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2017 Feb 28;42(2):233-235. doi: 10.11817/j.issn.1672-7347.2017.02.019.
Neuroblastoma is an embryonal tumor of the sympathetic nervous system, arising during fetal or early post-natal life from sympathetic cells derived from the neural crest. A 9-day-old boy was diagnosed as adrenal neuroblastoma with liver metastasis by biopsy. After 6 years of follow-up with ultrasound observation, the boy presents a process of spontaneous recovery without any special treatment. Spontaneous regression of cancer is defined as the decrease in size or disappearance of a primary tumor or metastatic disease without therapeutic intervention. Neuroblastoma is known to show the highest rate of spontaneous regression among malignant tumors. A better understanding of the mechanisms for spontaneous regression might help to identify optimal therapeutic approaches for patients with these tumors.
神经母细胞瘤是一种交感神经系统的胚胎性肿瘤,在胎儿期或出生后早期由神经嵴衍生的交感细胞发生。一名9天大的男婴经活检被诊断为肾上腺神经母细胞瘤伴肝转移。经过6年的超声随访观察,该男婴呈现出自发恢复过程,未接受任何特殊治疗。癌症的自发消退定义为在没有治疗干预的情况下,原发肿瘤或转移性疾病的大小减小或消失。已知神经母细胞瘤在恶性肿瘤中自发消退率最高。更好地了解自发消退的机制可能有助于为这些肿瘤患者确定最佳治疗方法。