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儿童口腔扁平苔藓:病例系列

Oral lichen planus in childhood: a case series.

作者信息

Cascone Marco, Celentano Antonio, Adamo Daniela, Leuci Stefania, Ruoppo Elvira, Mignogna Michele D

机构信息

Department of Neurosciences, Reproductive and Odontostomatological Sciences, University Federico II of Naples, Naples, Italy.

出版信息

Int J Dermatol. 2017 Jun;56(6):641-652. doi: 10.1111/ijd.13571. Epub 2017 Mar 3.

Abstract

BACKGROUND

Although the exact incidence of pediatric oral lichen planus (OLP) is unknown, the oral mucosa seems to be less commonly involved, and the clinical presentation is often atypical. The aim of the study is to present a case series of OLP in childhood.

METHODS

From our database, we retrospectively selected and analyzed the clinical data of OLP patients under the age of 18 where the diagnosis had been confirmed by histopathological analysis.

RESULTS

The case series from our database shows eight patients, four males and four females. The mean (±SD) age at the time of diagnosis of the disease was 13.5 (±2.73) years, ranging in age from 9 to 17. Clinically, a reticular pattern was present in six patients (75%), and the tongue was the most commonly involved oral site (six cases, 75%). We also report the first case of OLP in a 9-year-old girl affected by autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy.

CONCLUSIONS

We report the largest case series of pediatric OLP published in literature thus far. Differences in the disease between adults and pediatric patients have been detected, but further investigation and a larger case series are needed to establish any detailed differences in clinical outcomes.

摘要

背景

尽管儿童口腔扁平苔藓(OLP)的确切发病率尚不清楚,但口腔黏膜受累似乎较少见,且临床表现往往不典型。本研究的目的是呈现一组儿童OLP病例系列。

方法

从我们的数据库中,我们回顾性选择并分析了18岁以下经组织病理学分析确诊为OLP患者的临床资料。

结果

我们数据库中的病例系列显示有8例患者,4例男性和4例女性。疾病诊断时的平均(±标准差)年龄为13.5(±2.73)岁,年龄范围为9至17岁。临床上,6例患者(75%)出现网状型,舌是最常受累的口腔部位(6例,75%)。我们还报告了首例患自身免疫性多内分泌腺病-念珠菌病-外胚层营养不良的9岁女孩发生OLP的病例。

结论

我们报告了迄今为止文献中发表的最大规模的儿童OLP病例系列。已发现成人和儿童患者在该疾病上存在差异,但需要进一步研究和更大规模的病例系列来确定临床结局的任何详细差异。

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