Manasse Stephanie M, Flack Daniel, Dochat Cara, Zhang Fengqing, Butryn Meghan L, Forman Evan M
Drexel University, Department of Psychology, Philadelphia, PA, United States.
Drexel University, Department of Psychology, Philadelphia, PA, United States.
Appetite. 2017 Jun 1;113:193-199. doi: 10.1016/j.appet.2017.02.042. Epub 2017 Mar 1.
Behavioral weight loss (BWL) treatments result in suboptimal weight losses for many individuals. Impulsivity appears to be a maintenance factor of obesity, yet few studies have examined impulsivity as a predictor of outcomes from BWL. We examined specific facets of impulsivity (inhibitory control and delay discounting) as moderators of outcome in BWL. Overweight adults (n = 190) were randomized to standard behavioral treatment (SBT) or acceptance-based behavioral treatment (ABT). We hypothesized that impulsivity would be inversely associated with weight loss, and that the association between impulsivity and outcome would be attenuated in the ABT condition. Poorer general inhibitory control predicted lower percent weight lost at 12 months across conditions at the trend level (b = -0.003, p = 0.06). The negative impact of low inhibitory control on weight loss was attenuated by assignment to ABT versus SBT (b = 0.004, p = 0.03). Treatment condition, at trend level, also moderated the impact of delay discounting (b = -0.011, p = .098) and food-specific inhibitory control (b = 0.003, p = 0.06) on percent weight loss such that those with greater impulsivity benefitted most from ABT. Results reveal a potential pattern that impulsivity reduces benefit derived from SBT but not ABT. Further research on the moderating effect of impulsivity is necessary to inform the development of targeted treatments for clinically meaningful subtypes of patients.
行为减肥(BWL)治疗对许多人来说减肥效果并不理想。冲动似乎是肥胖的一个维持因素,但很少有研究将冲动作为BWL治疗结果的预测指标。我们研究了冲动的具体方面(抑制控制和延迟折扣)作为BWL治疗结果的调节因素。超重成年人(n = 190)被随机分为标准行为治疗(SBT)或基于接纳的行为治疗(ABT)。我们假设冲动与体重减轻呈负相关,并且在ABT条件下,冲动与治疗结果之间的关联会减弱。较差的一般抑制控制在趋势水平上预测了跨条件下12个月时较低的体重减轻百分比(b = -0.003,p = 0.06)。与SBT相比,分配到ABT可减轻低抑制控制对体重减轻的负面影响(b = 0.004,p = 0.03)。在趋势水平上,治疗条件也调节了延迟折扣(b = -0.011,p = 0.098)和食物特异性抑制控制(b = 0.003,p = 0.06)对体重减轻百分比的影响,使得冲动性较高的人从ABT中获益最多。结果揭示了一种潜在模式,即冲动会降低从SBT中获得的益处,但不会降低从ABT中获得的益处。有必要对冲动的调节作用进行进一步研究,以为针对具有临床意义的患者亚型开发针对性治疗提供依据。