State Key Laboratory of Oral Diseases and Department of Oral and Maxillofacial Surgery, West China College of Stomatology, Sichuan University, Chengdu, China.
State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Orthognathic & TMJ Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
J Craniomaxillofac Surg. 2019 Dec;47(12):1839-1847. doi: 10.1016/j.jcms.2019.10.003. Epub 2019 Oct 23.
This study aimed to compare the effectiveness and feasibility of inverted-L osteotomy (ILO) and sagittal split ramus osteotomy (SSRO) on obstructive sleep apnea (OSA) treatment. According to different surgery procedures, 28 OSA patients who underwent maxillomandibular advancement (MMA) were divided into 2 groups (group A: ILO, n = 9; group B: SSRO, n = 19). Polysomnography (PSG) and Epworth sleepiness scale (ESS) on T0, T1and T2 were used to evaluate the effectiveness of OSA treatments. Patients' airway structures and facial appearances were also evaluated. From T0 to T1, the mean apnea-hypopnea index (AHI,/per hour) dropped from 69.2 ± 8.4 to11.2 ± 2.4 (P < 0.01) in group A and from 54.6 ± 14.6 to 9.4 ± 5.4 (P < 0.01) in group B; LSpO2 (lowest pulse oxygen saturation, %) increased from 66.5 ± 7.7% to 88.2 ± 4.6 (P < 0.01) and from 76.6 ± 10.7%to 89.4 ± 2.4% (P < 0.01) while the mean ESS score decreased by 51% in group A and 44% in group B. Most patients (group A: 88.9%; group B: 84.3%) were satisfied with their postoperative appearance. Mild relapse was observed in both groups on T2. This study concluded that MMA containing ILO and MMA containing SSRO are both feasible and effective for selected OSA patients.
本研究旨在比较反向 L 型截骨术(ILO)和矢状劈开截骨术(SSRO)治疗阻塞性睡眠呼吸暂停(OSA)的效果和可行性。根据不同的手术程序,将 28 名接受下颌骨前伸术(MMA)的 OSA 患者分为 2 组(A 组:ILO,n=9;B 组:SSRO,n=19)。使用多导睡眠图(PSG)和 Epworth 嗜睡量表(ESS)于 T0、T1 和 T2 评估 OSA 治疗的效果。还评估了患者的气道结构和面部外观。从 T0 到 T1,A 组的平均呼吸暂停低通气指数(AHI,/小时)从 69.2±8.4 降至 11.2±2.4(P<0.01),B 组从 54.6±14.6 降至 9.4±5.4(P<0.01);LSpO2(最低脉搏血氧饱和度,%)从 66.5±7.7%增加到 88.2±4.6(P<0.01)和 76.6±10.7%增加到 89.4±2.4%(P<0.01),而 A 组的 ESS 评分平均降低了 51%,B 组降低了 44%。大多数患者(A 组:88.9%;B 组:84.3%)对术后外观满意。两组在 T2 时均观察到轻度复发。本研究得出结论,包含 ILO 和 SSRO 的 MMA 对于选定的 OSA 患者都是可行且有效的。