Dirican Nigar, Demirci Seden, Cakir Munire
Department of Chest Diseases, Faculty of Medicine, Suleyman Demirel University, 32260, Isparta, Turkey.
Department of Neurology, Faculty of Medicine, Suleyman Demirel University, Isparta, Turkey.
Acta Neurol Belg. 2017 Jun;117(2):531-536. doi: 10.1007/s13760-017-0764-0. Epub 2017 Mar 3.
Migraine and asthma are comorbid chronic disorders with episodic attacks thought to involve inflammatory and neurological mechanisms. The objective of the present study is to investigate the relationship of asthma features between the asthma patients with migraine and those without migraine headache. A cross-sectional study was conducted from October 2015 to June 2016. Physician-diagnosed asthma patients aged 18 years and above were included. Demographic data, pulmonary function test and treatment of asthma were recorded. Asthma control was assessed using the asthma control test (ACT) and asthma control questionnaire (ACQ). The diagnosis of migraine was made by the neurologist with face-to face examinations based on the International Classification of Headache Disorders, third edition beta (ICHD-III-beta) criteria. Data about the age at onset, frequency of headache attacks, duration of headache attack, the presence of aura, and severity of headache were recorded. The severity of headache was evaluated using visual analogue scale (VAS). Overall 121 asthma patients were included in this study. Migraine was found to be present in 32 (26.4%) of patients. No statistically significant difference was found between asthma group and asthma with migraine groups in terms of pulmonary function test parameters. The mean ACT score in asthma with migraine patients group was significantly lower than the asthma groups. Morever, in the group asthma with migraine, a negative significant correlations were found between ACT scores with VAS scores. This study demonstrates that migraine headache may be associated with poor asthma control. On the other hand, it should not be forgotten that ACT is a subjective test and can be affected from by many clinical parameters.
偏头痛和哮喘是共病的慢性疾病,其发作性发作被认为涉及炎症和神经机制。本研究的目的是调查偏头痛哮喘患者与无偏头痛哮喘患者之间哮喘特征的关系。2015年10月至2016年6月进行了一项横断面研究。纳入年龄在18岁及以上的医生诊断的哮喘患者。记录人口统计学数据、肺功能测试和哮喘治疗情况。使用哮喘控制测试(ACT)和哮喘控制问卷(ACQ)评估哮喘控制情况。偏头痛的诊断由神经科医生根据《国际头痛疾病分类》第三版beta版(ICHD-III-beta)标准进行面对面检查做出。记录有关发病年龄、头痛发作频率、头痛发作持续时间、先兆的存在以及头痛严重程度的数据。使用视觉模拟量表(VAS)评估头痛的严重程度。本研究共纳入121例哮喘患者。发现32例(26.4%)患者患有偏头痛。哮喘组和偏头痛哮喘组在肺功能测试参数方面未发现统计学上的显著差异。偏头痛哮喘患者组的平均ACT评分显著低于哮喘组。此外,在偏头痛哮喘组中,ACT评分与VAS评分之间存在显著负相关。本研究表明偏头痛可能与哮喘控制不佳有关。另一方面,不应忘记ACT是一项主观测试,可能会受到许多临床参数的影响。