[大剂量化疗后自体骨髓移植治疗小细胞支气管癌]
[High-doses chemotherapy followed by bone marrow autograft in the treatment of small cell bronchial cancer].
作者信息
Pico J L, Baume D, Ostronoff M, Beaujean F, Gouyette A, Le Chevalier T, Arriagada R, Rebattu P, Hayat M
机构信息
Institut Gustave-Roussy, Villejuif, France.
出版信息
Bull Cancer. 1987;74(5):587-95.
PMID:2825862
Abstract
Nineteen patients were treated with high dose chemotherapy followed by an autologous bone marrow transplantation. The chemotherapy regimen was an association of BCNU, procarbazine, etoposide, melphalan. Six patients had a progressive disease; 4 short-term complete remissions were observed. In 13 responding patients, 6 maintained complete remissions were noted.
摘要
19名患者接受了大剂量化疗，随后进行自体骨髓移植。化疗方案为卡氮芥、丙卡巴肼、依托泊苷、美法仑联合使用。6名患者病情进展；观察到4例短期完全缓解。在13名有反应的患者中，有6名维持完全缓解。
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