Lee Michael S, Park Kyung Woo, Shlofmitz Evan, Shlofmitz Richard A
Division of Cardiology, UCLA Medical Center, Los Angeles, California.
Department of Internal Medicine and Cardiovascular Center, Seoul National University Hospital, Seoul, Republic of Korea.
Am J Cardiol. 2017 May 1;119(9):1320-1323. doi: 10.1016/j.amjcard.2017.01.025. Epub 2017 Feb 10.
We evaluated the outcomes of patients with severe coronary artery calcification (CAC) who underwent rotational atherectomy (RA) and orbital atherectomy (OA). Severe CAC increases the complexity of percutaneous coronary intervention (PCI) because of the difficulty in optimizing stent expansion, leading to worse clinical outcomes. Both devices are effective treatment strategies for severe CAC. No comparisons have been performed to evaluate the clinical outcomes after RA and OA. The outcomes of 67 patients with severe CAC who underwent RA from July 2012 to June 2015 and 60 patients who underwent OA from February 2014 to September 2016 were evaluated. The primary end point was the rate of 30-day major adverse cardiac and cerebrovascular events, comprising cardiac death, myocardial infarction, target vessel revascularization, and stroke. The primary end point was similar in the RA and OA groups (6% vs 6%, p >0.9), as were the individual end points of death (0% vs 2%, p = 0.8), myocardial infarction (6% vs 4%, p = 0.7), target vessel revascularization (0% vs 0%, p >0.9), and stroke (0% vs 0%, p >9). Procedural success was achieved in all patients. Angiographic complications were uncommon in both groups. No patient had stent thrombosis. In conclusion, both RA and OA are safe and effective for the treatment of severe CAC as they provided similar clinical outcomes at short-term follow-up.
我们评估了接受旋磨术(RA)和准分子激光冠状动脉斑块消蚀术(OA)的严重冠状动脉钙化(CAC)患者的治疗结果。严重的CAC会增加经皮冠状动脉介入治疗(PCI)的复杂性,因为优化支架扩张存在困难,从而导致更差的临床结果。这两种设备都是治疗严重CAC的有效策略。尚未进行比较来评估RA和OA后的临床结果。对2012年7月至2015年6月接受RA的67例严重CAC患者和2014年2月至2016年9月接受OA的60例患者的治疗结果进行了评估。主要终点是30天主要不良心脑血管事件的发生率,包括心源性死亡、心肌梗死、靶血管血运重建和中风。RA组和OA组的主要终点相似(6%对6%,p>0.9),死亡(0%对2%,p = 0.8)、心肌梗死(6%对4%,p = 0.7)、靶血管血运重建(0%对0%,p>0.9)和中风(0%对0%,p>0.9)的个体终点也相似。所有患者均获得手术成功。两组血管造影并发症均不常见。没有患者发生支架血栓形成。总之,RA和OA在治疗严重CAC方面都是安全有效的,因为它们在短期随访中提供了相似的临床结果。