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自发性冠状动脉假性动脉瘤的诊断与治疗:具有潜在重大临床意义的罕见异常情况。

Diagnosis and treatment of spontaneous coronary artery pseudoaneurysm: Rare anomaly with potentially significant clinical implications.

作者信息

Kar Subrata, Webel Richard R

机构信息

Division of Cardiovascular Medicine, Texas Tech University Health Sciences Center, Paul L. Foster School of Medicine, El Paso, Texas.

Department of Medicine, University of Missouri School of Medicine, Columbia, Missouri.

出版信息

Catheter Cardiovasc Interv. 2017 Oct 1;90(4):589-597. doi: 10.1002/ccd.26997. Epub 2017 Mar 4.

Abstract

Spontaneous coronary artery pseudoaneurysm (PSA, false aneurysm) is an extremely rare occurrence with the precise incidence unknown. It is defined as an outwardly bulging monolayer or double layer within the coronary artery that lacks all 3 layers (intima, media, and adventitia) of the arterial wall. Coronary PSA commonly occurs from arterial dissection or perforation induced by catheter intervention, infection, pregnancy, or trauma. Traumatic dissection or perforation of the coronary artery after a percutaneous coronary intervention (PCI) remains the most common cause. Such cases may progress to myocardial ischemia, acute myocardial infarction, or acute coronary artery rupture causing death from cardiac tamponade. Intravascular ultrasound or cardiac computed tomography may aid in the diagnosis. Treatment options include PCI with a covered stent, bare or drug-eluting stent, coil embolization, coronary artery bypass graft with isolation of the PSA, or conservative management with vigilant clinical follow-up. In this review, we sought to describe the diagnosis, etiology, treatment, and the limited literature on spontaneous coronary artery PSA. © 2017 Wiley Periodicals, Inc.

摘要

自发性冠状动脉假性动脉瘤(PSA,即假性动脉瘤)极为罕见,确切发病率尚不清楚。它被定义为冠状动脉内向外膨出的单层或双层结构,缺乏动脉壁的所有三层结构(内膜、中膜和外膜)。冠状动脉PSA通常由导管介入、感染、妊娠或创伤引起的动脉夹层或穿孔所致。经皮冠状动脉介入治疗(PCI)后冠状动脉的创伤性夹层或穿孔仍是最常见的原因。此类病例可能进展为心肌缺血、急性心肌梗死或急性冠状动脉破裂,导致心脏压塞死亡。血管内超声或心脏计算机断层扫描有助于诊断。治疗选择包括使用覆膜支架、裸支架或药物洗脱支架进行PCI、弹簧圈栓塞、隔离PSA的冠状动脉旁路移植术,或进行密切临床随访的保守治疗。在本综述中,我们试图描述自发性冠状动脉PSA的诊断、病因、治疗以及有限的相关文献。© 2017威利期刊公司

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