Raghavan D, Mackintosh J F, Fox R M, Rogers J, Duval P, Besser M
Urological Cancer Research Unit, Royal Prince Alfred Hospital, Camperdown, Australia.
Br J Urol. 1987 Oct;60(4):364-7. doi: 10.1111/j.1464-410x.1987.tb04987.x.
Long-term disease-free survival (78 + and 31 + months) has been achieved in two of four patients treated for brain metastases from non-seminomatous germ cell tumours between 1980 and 1984. The incidence of cerebral metastases among 101 patients seen over the 5-year period was 4%. The encouraging results from the use of combined modality treatment, incorporating cisplatin-based chemotherapy, whole brain irradiation and surgery, are reviewed.
1980年至1984年间,接受治疗的4例非精原细胞瘤性生殖细胞肿瘤脑转移患者中有2例实现了长期无病生存(分别为78个月以上和31个月以上)。在5年期间诊治的101例患者中,脑转移的发生率为4%。本文回顾了采用联合治疗模式(包括以顺铂为基础的化疗、全脑放疗和手术)所取得的令人鼓舞的结果。