Dumont R, Bui Quoc E, Ajzenfisz S, Bourdon O, Prot-Labarthe S
Inserm, U1123, ECEVE, département de pharmacie, 48, boulevard Sérurier, 75019 Paris, France; Coordination de la gestion des risques associés aux soins et à la prise en charge médicamenteuse, AP-HP, hôpital universitaire Robert-Debré, 48, boulevard Sérurier, 75019 Paris, France.
Service d'ophtalmologie, 48, boulevard Sérurier, 75019 Paris, France; Coordination de la gestion des risques associés aux soins et à la prise en charge médicamenteuse, AP-HP, hôpital universitaire Robert-Debré, 48, boulevard Sérurier, 75019 Paris, France.
Arch Pediatr. 2017 Apr;24(4):417-420. doi: 10.1016/j.arcped.2016.12.012. Epub 2017 Mar 1.
Mydriatic eye drops are indicated for ophthalmologic exams (fundus and cycloplegic effect for refraction diagnosis). Their use must be optimal to avoid adverse reactions. This is even more important in pediatrics, because few clinical studies were conducted in this population during drug development. We reviewed the use of mydriatic eye drops, gathering information from the Summary of Product Characteristics (SPC) from the Theriaque database (CNHIM) and the manufacturers' information, in terms of dose, concentration and volume administered, age limit indications, recommendations for administration, and our local practice. This tool is useful in our hospital for physicians, pharmacists, and nurses but could be also useful for all healthcare providers using mydriatic eye drops for children.
散瞳眼药水适用于眼科检查（用于眼底检查以及在屈光诊断中产生睫状肌麻痹作用）。必须优化其使用以避免不良反应。这在儿科中更为重要，因为在药物研发过程中针对该人群开展的临床研究较少。我们回顾了散瞳眼药水的使用情况，从Theriaque数据库（CNHIM）的产品特性摘要（SPC）以及制造商信息中收集了有关给药剂量、浓度和体积、年龄限制适应症、给药建议以及我们当地的实际应用等方面的信息。该工具对我们医院的医生、药剂师和护士很有用，但对于所有给儿童使用散瞳眼药水的医疗服务提供者也可能有用。
