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一家教学医院新设立的器官移植项目的初步成果。

Preliminary Results of a Newly Established Organ Transplantation Program in a Teaching Hospital.

作者信息

Momani Hammam, Algeizawi Samer, Shamoun Badia, Taha Atef Abu, Alshakhatreh Hamed, Breizat Abdel-Hadi

机构信息

Department of Surgery, Hepatopancreatobiliary and Organ Transplant Unit, Al-Basheer Hospital, Ministry of Health, Amman, Jordan.

出版信息

Exp Clin Transplant. 2017 Feb;15(Suppl 1):110-112. doi: 10.6002/ect.mesot2016.O106.

Abstract

OBJECTIVES

End-stage renal disease is the complete failure of kidney function; kidney transplant offers the best survival advantage. We analyzed data from Al-Basheer Hospital's newly established transplant program and present our kidney transplant results from the first year of operation.

MATERIALS AND METHODS

Between April 2015 and June 2016, 20 kidney transplants were performed (19 living-related donors and 1 deceased donor). We assessed the demographic data, surgical techniques employed, complications, immunosuppressive drugs used, and graft and patient survival rates. The mean recipient age was 32.8 years. There were 10 male and 10 female patients. Two patients underwent preemptive transplant, and 18 were on hemodialysis. Preparation of the donor and recipient employed an established transplant protocol. Induction immunosuppression therapy was used in 13.65% of patients. The left kidney was used from all living donors, and the right kidney was harvested from the deceased donor. The total ischemia time in the living-donor grafts ranged from 30 to 53 minutes; in the deceased donor, the ischemia time was 90 minutes. Intraoperative Doppler ultrasonography was used in most cases.

RESULTS

There was no donor mortality, and no significant donor complications occurred, either intraoperatively or postoperatively. There was no recipient mortality, but there were complications in 6 patients. Intraoperative complications were reported in 2 patients: 1 with renal artery thrombosis and the other with external iliac artery dissection. Postoperative complications were reported in 4 patients: slow graft function in 1 patient with thrombotic thrombocytopenic purpura, 1 patient with acute cellular rejection treated with intravenous immunoglobulin, 1 patient with cytomegalovirus gastroenteritis, and 1 patient treated for varicella pneumonitis. The follow-up ranged from 1 week to 13 months.

CONCLUSIONS

The first-year outcomes for our newly established transplant program at Al-Basheer Hospital are comparable to those of well-established programs.

摘要

目的

终末期肾病是肾功能的完全衰竭;肾移植具有最佳的生存优势。我们分析了阿尔 - 巴希尔医院新设立的移植项目的数据,并呈现了我们移植项目第一年的肾移植结果。

材料与方法

在2015年4月至2016年6月期间,进行了20例肾移植手术(19例活体亲属供体和1例尸体供体)。我们评估了人口统计学数据、所采用的手术技术、并发症、使用的免疫抑制药物以及移植物和患者的生存率。受者的平均年龄为32.8岁。有10名男性和10名女性患者。2例患者接受了先发制人移植,18例患者接受血液透析。供体和受体的准备采用既定的移植方案。13.65%的患者使用了诱导免疫抑制治疗。所有活体供体均使用左肾,尸体供体的右肾被摘取。活体供体移植物的总缺血时间为30至53分钟;尸体供体的缺血时间为90分钟。大多数病例术中使用了多普勒超声检查。

结果

没有供体死亡,术中或术后也没有发生严重的供体并发症。没有受者死亡,但有6例患者出现了并发症。2例患者报告了术中并发症:1例肾动脉血栓形成,另1例髂外动脉夹层。4例患者报告了术后并发症:1例血栓性血小板减少性紫癜患者移植物功能缓慢,1例急性细胞排斥反应患者接受静脉注射免疫球蛋白治疗,1例巨细胞病毒性胃肠炎患者,1例水痘肺炎患者。随访时间为1周至13个月。

结论

阿尔 - 巴希尔医院新设立的移植项目第一年的结果与成熟项目的结果相当。

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