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吲哚美辛诱发、前列腺素缓解右位主动脉弓伴左位动脉导管的主动脉缩窄:一例报告

Indomethacin induced and prostaglandin relieved coarctation of the aorta in right aortic arch with left arterial duct: a case report.

作者信息

Golden-Plotnik Stevi, Rosenberg Herschel C, Altamirano-Diaz Luis A

机构信息

Department of Paediatrics,Western University,London,Ontario,Canada.

出版信息

Cardiol Young. 2017 Jul;27(5):1026-1029. doi: 10.1017/S1047951117000075. Epub 2017 Mar 6.

Abstract

We describe the case of an infant with DiGeorge syndrome born with a right aortic arch and left arterial duct. Despite the remote location of the right aortic arch from the left arterial duct, he developed coarctation of the aorta during treatment with indomethacin. This was relieved by prostaglandin treatment. This case highlights the fact that, even in the absence of an arterial duct, ductal tissue can still be present in the aorta, and cause coarctation when exposed to indomethacin. We also demonstrate the utility of prostaglandin for relief of this type of obstruction.

摘要

我们描述了一例患有DiGeorge综合征的婴儿,其出生时伴有右位主动脉弓和左动脉导管。尽管右位主动脉弓与左动脉导管位置较远,但他在接受吲哚美辛治疗期间发生了主动脉缩窄。经前列腺素治疗后症状缓解。该病例凸显了这样一个事实,即即使没有动脉导管,主动脉中仍可能存在导管组织,且在接触吲哚美辛时会导致主动脉缩窄。我们还证明了前列腺素对缓解此类梗阻的效用。

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