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妊娠滋养细胞疾病管理中的手术治疗

Surgery in the management of gestational trophoblastic disease.

作者信息

Green-Thompson R W

出版信息

Baillieres Clin Obstet Gynaecol. 1987 Jun;1(2):293-317. doi: 10.1016/s0950-3552(87)80056-1.

DOI:10.1016/s0950-3552(87)80056-1
PMID:2826060
Abstract

The role of surgery in GTD has been outlined and explained in detail. The importance of accurate diagnosis, clinical assessment, patient resuscitation and support, individualization of management and patient selection has been stressed. The prognosis for patients with GTD is now a successful outcome in 70-100% of cases, depending on the risk factors present. Cerebral lesions still present a poor prognosis especially if developed while on chemotherapy. Advances have been made in the management of choriocarcinoma since the established use of chemotherapy. Surgery plays an important adjunctive role in the improved prognosis of the disease. This has been discussed in depth. Modern surgical methods, for example selective embolization of vessels supplying vascular bleeding tumours, have improved patients' prospects. The management of hydatidiform mole has been largely resolved by the introduction of suction curettage. It is the method of choice for the evacuation of the uterus in molar disease. Controversies have been discussed and a balanced assessment has been attempted to give the reader a realistic guide to patient management when presented with these problems. Important sequelae and complications of GTD have been presented and measures of prevention and management have been advanced. It is hoped that all this will further improve the management of the patient with GTD in the future.

摘要

手术在妊娠滋养细胞疾病(GTD)中的作用已被详细概述和解释。强调了准确诊断、临床评估、患者复苏与支持、管理个体化以及患者选择的重要性。GTD患者的预后目前在70% - 100%的病例中是成功的,这取决于存在的风险因素。脑病变的预后仍然很差,尤其是在化疗期间发生时。自从确立化疗的应用以来,绒毛膜癌的管理取得了进展。手术在改善该疾病的预后方面起着重要的辅助作用。这已被深入讨论。现代手术方法,例如对供应血管出血性肿瘤的血管进行选择性栓塞,改善了患者的前景。通过引入吸刮术,葡萄胎的管理在很大程度上得到了解决。它是处理葡萄胎疾病时清空子宫的首选方法。已经讨论了争议点,并尝试进行了平衡评估,以便在读者遇到这些问题时为患者管理提供现实的指导。已经介绍了GTD的重要后遗症和并发症,并提出了预防和管理措施。希望所有这些将在未来进一步改善GTD患者的管理。

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