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Recombinant factor VIIa for variceal bleeding in liver cirrhosis: still only a hope.

作者信息

Qi Xingshun, Ye Chun, Guo Xiaozhong

机构信息

Liver Cirrhosis Study Group, Department of Gastroenterology, General Hospital of Shenyang Military Area, Shenyang, China.

Department of General Surgery, General Hospital of Shenyang Military Area, Shenyang, China.

出版信息

Arch Med Sci. 2017 Mar 1;13(2):496-499. doi: 10.5114/aoms.2017.65331. Epub 2017 Jan 23.

DOI:10.5114/aoms.2017.65331
PMID:28261306
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5332460/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/712f/5332460/3adda27dc2f2/AMS-13-29201-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/712f/5332460/3adda27dc2f2/AMS-13-29201-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/712f/5332460/3adda27dc2f2/AMS-13-29201-g001.jpg

相似文献

1
Recombinant factor VIIa for variceal bleeding in liver cirrhosis: still only a hope.重组凝血因子VIIa用于肝硬化静脉曲张出血：仍只是一种希望。
Arch Med Sci. 2017 Mar 1;13(2):496-499. doi: 10.5114/aoms.2017.65331. Epub 2017 Jan 23.
2
Recombinant factor VIIa for variceal bleeding in patients with advanced cirrhosis: A randomized, controlled trial.重组凝血因子VIIa用于晚期肝硬化患者静脉曲张出血的随机对照试验。
Hepatology. 2008 May;47(5):1604-14. doi: 10.1002/hep.22216.
3
Recombinant factor VIIa for upper gastrointestinal bleeding in patients with cirrhosis: a randomized, double-blind trial.重组凝血因子VIIa用于肝硬化患者上消化道出血的治疗：一项随机双盲试验
Gastroenterology. 2004 Oct;127(4):1123-30. doi: 10.1053/j.gastro.2004.07.015.
4
Recombinant factor VIIa for variceal bleeding: when, why, and how?重组凝血因子VIIa用于静脉曲张出血：何时、为何以及如何使用？
Gastroenterology. 2005 Apr;128(4):1150-1; author reply 1151. doi: 10.1053/j.gastro.2005.02.046.
5
Effect of recombinant Factor VIIa on outcome of acute variceal bleeding: an individual patient based meta-analysis of two controlled trials.重组 FVIIa 对急性静脉曲张出血结局的影响：两项对照试验的个体患者荟萃分析。
J Hepatol. 2014 Aug;61(2):252-9. doi: 10.1016/j.jhep.2014.03.035. Epub 2014 Apr 5.
6
Current approaches to the management of patients with liver cirrhosis who have acute esophageal variceal bleeding.肝硬化合并急性食管静脉曲张出血患者的当前管理方法。
Curr Med Res Opin. 2016;32(3):467-75. doi: 10.1185/03007995.2015.1124846. Epub 2016 Jan 25.
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J Gastroenterol Hepatol. 2004 Sep;19(9):1042-51. doi: 10.1111/j.1440-1746.2004.03383.x.
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Role of the von Willebrand factor and the VITRO score as predictors for variceal bleeding in patients with hepatitis C-related cirrhosis.血管性血友病因子及VITRO评分在丙型肝炎相关肝硬化患者静脉曲张出血预测中的作用
Eur J Gastroenterol Hepatol. 2019 Feb;31(2):241-247. doi: 10.1097/MEG.0000000000001272.
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A cerebrovascular event after single-dose administration of recombinant factor VIIa in a patient with esophageal variceal bleeding.一名食管静脉曲张出血患者单次注射重组凝血因子VIIa后发生脑血管事件。
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Safety and efficacy of dual antiplatelet therapy after percutaneous coronary interventions in patients with end-stage liver disease.终末期肝病患者经皮冠状动脉介入治疗后双重抗血小板治疗的安全性和有效性。
World J Cardiol. 2021 Nov 26;13(11):599-607. doi: 10.4330/wjc.v13.i11.599.
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No Benefit of Hemostatic Drugs on Acute Upper Gastrointestinal Bleeding in Cirrhosis.肝硬化急性上消化道出血中止血药物无效。
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本文引用的文献

1
Activated recombinant factor VIIa should not be used in patients with refractory variceal bleeding: it is mostly ineffective, is expensive, and may rarely cause serious adverse events.活化重组凝血因子VIIa不应应用于难治性静脉曲张出血患者：它大多无效，价格昂贵，且可能极少引起严重不良事件。
Hepatology. 2014 Nov;60(5):1786-8. doi: 10.1002/hep.27363. Epub 2014 Oct 2.
2
Rational Use of Recombinant Factor VIIa in Clinical Practice.重组凝血因子VIIa在临床实践中的合理应用
Indian J Hematol Blood Transfus. 2014 Jun;30(2):85-90. doi: 10.1007/s12288-013-0240-9. Epub 2013 Feb 23.
3
Effect of recombinant Factor VIIa on outcome of acute variceal bleeding: an individual patient based meta-analysis of two controlled trials.
胸腹壁蜘蛛痣及皮下侧支血管对肝硬化结局的影响
Arch Med Sci. 2019 Mar;15(2):434-448. doi: 10.5114/aoms.2018.74788. Epub 2018 Mar 28.
重组 FVIIa 对急性静脉曲张出血结局的影响：两项对照试验的个体患者荟萃分析。
J Hepatol. 2014 Aug;61(2):252-9. doi: 10.1016/j.jhep.2014.03.035. Epub 2014 Apr 5.
4
How to use a subgroup analysis: users' guide to the medical literature.如何进行亚组分析：医学文献使用指南。
JAMA. 2014;311(4):405-11. doi: 10.1001/jama.2013.285063.
5
Recombinant factor VIIa as haemostatic therapy in advanced liver disease.重组凝血因子VIIa在晚期肝病止血治疗中的应用
Blood Transfus. 2013 Oct;11(4):487-90. doi: 10.2450/2012.0066-12. Epub 2012 Oct 10.
6
Human recombinant activated factor VII for upper gastrointestinal bleeding in patients with liver diseases.重组人活化凝血因子 VII 用于肝病患者上消化道出血的治疗
Cochrane Database Syst Rev. 2012 Mar 14;2012(3):CD004887. doi: 10.1002/14651858.CD004887.pub3.
7
Haemophilia in the developing countries: the Iranian experience.发展中国家的血友病：伊朗的经验。
Arch Med Sci. 2010 Mar 1;6(1):83-9. doi: 10.5114/aoms.2010.13512. Epub 2010 Mar 9.
8
Systematic review: benefits and harms of in-hospital use of recombinant factor VIIa for off-label indications.系统评价：院内使用重组 VII 因子治疗超适应证的获益和危害。
Ann Intern Med. 2011 Apr 19;154(8):529-40. doi: 10.7326/0003-4819-154-8-201104190-00004.
9
Safety of recombinant activated factor VII in randomized clinical trials.重组活化因子 VII 在随机临床试验中的安全性。
N Engl J Med. 2010 Nov 4;363(19):1791-800. doi: 10.1056/NEJMoa1006221.
10
Is a subgroup effect believable? Updating criteria to evaluate the credibility of subgroup analyses.亚组效应可信吗？更新评估亚组分析可信度的标准。
BMJ. 2010 Mar 30;340:c117. doi: 10.1136/bmj.c117.